Results 71 to 80 of about 8,817,528 (292)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A Strong Magnetic Field Alters the Activity and Selectivity of the CO2RR by Restraining C–C Coupling

, 2023
As an external field, a magnetic field can change the electrocatalytic activity of catalysts through various effects. Among them, electron spin polarization on the catalyst surface has attracted much attention.
Yafei Qu, Peichen Wang, Jinwei Tu, Xiangfu Meng, Lin Hu, Qianwang Chen, Wei Zheng   +6 more
core   +1 more source

Enhanced Effects of Intermittent Fasting by Magnetic Fields in Severe Diabetes

Research
Intermittent fasting (IF) is a convenient dietary intervention for multiple diseases, including type 2 diabetes. However, whether it can be used as a long-term antidiabetic approach is still unknown.
Ying Wang, Chuanlin Feng, Biao Yu, Junjun Wang, Weili Chen, Chao Song, Xinmiao Ji, Ruowen Guo, Guofeng Cheng, Hanxiao Chen, Xinyu Wang, Lei Zhang, Zhiyuan Li, Jialiang Jiang, Can Xie, Haifeng Du, Xin Zhang   +16 more
doaj   +1 more source

Investigation on the Parasitic Capacitance of High Frequency and High Voltage Transformers of Multi-Section Windings

IEEE Access, 2020
Resonant converters are widely used in high voltage applications thanks to the soft switching technologies. The high frequency and high voltage (HFHV) transformer is the most complicated and important part to boost the voltage by tens or hundreds of ...
Le Deng, Pengbo Wang, Xiaofeng Li, Houxiu Xiao, Tao Peng   +4 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Modeling and Measuring of Light Shift in Optically Pumped Atomic Magnetometers

IEEE Photonics Journal
The light shift is a significant error source of optically pumped atomic magnetometers (OPAMs), requiring accurate calculation or measurement to assess its impact on the accuracy of OPAMs.
Yuntian Zou, Xiangyang Zhou, Jiali Liu, Chi Fang, Jinghong Xu, Wei Quan, Liwei Jiang   +6 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Magnetic fields and cancer.

Environmental Health Perspectives, 1993
This letter is a response to an article by Savitz and Kaune, EHP 101:76-80. W-L wire code was applied to data from a 1988 Denver study, and an association was reported between high W-L wire code and childhood cancer. This author discusses several studies and provides explanations which weakens the argument that classification error resulted in an ...
openaire   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Emergent magnetic anisotropy in the cubic heavy-fermion metal CeIn3

npj Quantum Materials, 2017
Heavy fermion materials: Emergence of field-induced magnetic anisotropy Magnetic anisotropy emerges in structurally isotropic heavy fermion metals under large magnetic fields.
Philip J. W. Moll, Toni Helm, Shang-Shun Zhang, Cristian D. Batista, Neil Harrison, Ross D. McDonald, Laurel E. Winter, B. J. Ramshaw, Mun K. Chan, Fedor F. Balakirev, Bertram Batlogg, Eric D. Bauer, Filip Ronning   +12 more
doaj   +1 more source