Results 41 to 50 of about 372,562 (311)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Magnetic Stability Analysis for the Geodynamo [PDF]
Kinematic dynamo modelling addresses the growth of magnetic fields under the action of fluid flow, effected in the geophysical case by the action of the convecting electrically conducting outer core and magnetic diffusion. In this study, we prescribe the
Livermore, Philip
core
A Highly Sensitive Magnetic Field Sensor Based on a Tapered Microfiber
A compact all-fiber magnetic field sensor based on the combination of a magnetic fluid and a nonadiabatic microfiber is experimentally demonstrated. By using a fusion splicer combined with an additional flame brushing, the nonadiabatic microfiber, with ...
Zelong Ma +6 more
doaj +1 more source
Electrical Conductivity of Field-Structured Emulsions
The structure formation influence on various macroscopic properties of fluid–fluid disperse systems is poorly investigated. The present work deals with the experimental study of the charge transfer in emulsions whose dispersed phase droplets are arranged
Arthur R. Zakinyan +3 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The solar tachocline: a self-consistent model of magnetic confinement
In this dissertation we consider the dynamics of the solar interior, with particular focus on angular momentum balance and magnetic field confinement within the tachocline. In Part I we review current knowledge of the Sun's rotation.
core +1 more source
The dependence of magnetic relaxation on particle parameters, such as the size and anisotropy, has been conventionally discussed. In addition, the influences of external conditions, such as the intensity and frequency of the applied field, the ...
Satoshi Ota +4 more
doaj +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source

