Results 71 to 80 of about 4,467,203 (282)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Temperature and strain scaling laws for the critical current density in Nb(_3)Sn and Nb(_3)Al conductors in high magnetic fields [PDF]

open access: yes, 2001
Detailed, accurate measurements of critical current density and resistivity to determine the upper critical field have been made on a technological NbsAl conductor in magnetic fields up to 15 T, temperatures from 4.2 K up to the critical temperature and ...
Keys, Simon Alastair
core  

Structural Design and Transmission Performance Analysis of Double Modulated Coaxial Magnetic Gear

open access: yesJixie chuandong, 2019
Aiming at the problem of low transmission torque caused by the magnetic flux leakage phenomenon of the traditional magnetic gear permanent magnet,a coaxial magnetic gear model with double modulation structure is established based on the relative ...
Peng Wu, Zina Zhu, Kaiyuan Li
doaj  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Hybrid torque and SQUID magnetometry of individual magnetic nanotubes [PDF]

open access: yes, 2015
For the experiments presented in this thesis, a hybrid magnetometer consisting of a ultra sensitive Si cantilever and a nano-scale superconducting quantum interference device (nanoSQUID) sensitive enough to measure a single nanoscale magnetic particle ...
Buchter, Arne
core   +1 more source

双层实心异步磁力联轴器三维静态气隙磁场解析计算

open access: yesJixie chuandong, 2013
In order to obtain the spatial distribution of the 3-D static air-gap magnetic field in double-layer solid rotor asynchronous magnetic couplings,the 3-D analytical model of the air-gap magnetic field in the coupling is built based on the equivalent ...
杨超君, 徐燕飞, 陈晓平, 杜怿
doaj  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Safe Distance for Leukemia Risk Due to Magnetic Fields Caused by High-Voltage Power Lines Using Linear Regression Model

open access: yesInternational Journal of Environmental Health Engineering
Aim: Power transmission lines are considered sources with extremely low-frequency magnetic fields. According to previous studies, these types of electromagnetic fields impose adverse effects on the human health.
Afsaneh Amiri   +3 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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