Results 231 to 240 of about 219,781 (336)

DRD2 Deficiency Underlies Pituitary Adenoma Dependent on Escherichia coli Translocation from the Gut

Advanced Science, EarlyView.
Dopamine receptor D2 (DRD2) deficiency disrupts epithelial barrier integrity in both the gut and pituitary gland, facilitating translocation of gut‐derived Escherichia coli into pituitary tissue. Intratumoral E. coli are phagocytosed by microglia, triggering GSDMD‐dependent pyroptosis and HMGB1 release, which subsequently activates MAPK signaling to ...
Xian‐jun Su, Li Ma, Xi Xiong, Jun‐hua Meng, Qi Wu, Yu Zhang, Shu‐guang Dong, Yue‐fei Wang, Jin‐hu Wu, Qing‐yuan Zeng, Hong‐feng Zhang, Li‐li Li, Liang Meng, Min Peng, Xiao‐dong Huang, Li‐quan Wu, Xiong Wang   +16 more
wiley   +1 more source

Analysis on the Air-Gap Magnetic Field and Force of the Linear Synchronous Motor with Different Winding Distribution. [PDF]

Micromachines (Basel)
Bai J, Zhang L, Xu Y.
europepmc   +1 more source

A Supramolecular Ferroelectric With Two Sublattices and Polarization Dependent Conductivity

Advanced Science, EarlyView.
Ferroelectric behavior in a supramolecular material with two, independently switchable, sublattices is demonstrated. The sublattices can be associated with the two dipolar groups in the compound. Moreover, the polarization is found to couple to the charge transport in the material, giving rise to a switchable, directional conductivity.
H. Mager, M. Litterst, Sophia Klubertz, Shyamkumar V. Haridas, Oleksandr Shyshov, M. von Delius, M. Kemerink   +6 more
wiley   +1 more source

Optimal Design of Electromagnetic Absorber Based on Magnetic Field Directional Consistency. [PDF]

Materials (Basel)
Wang J, Lou J, Yang Q, Li R, Tan M, Yang M, Bao X.   +6 more
europepmc   +1 more source

A Plug‐and‐Play Volume Minimizing Micromixer

Advanced Science, EarlyView.
ABSTRACT Microscale fluid mixing has numerous applications where rapid and efficient mixing is required, including drug discovery, bio‐analysis and point‐of‐care diagnostics. Conventional soft lithography processes, however, make the integration of robust and reliable mixing difficult to implement in practice, especially across different flow rates ...
Kirill Kolesnik, Philipp Segeritz, Daniel J. Scott, David J. Collins   +3 more
wiley   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

Performance driven multi objective optimization of 2 MW integrated Pseudo Direct Drive permanent magnet synchronous wind generator. [PDF]

Sci Rep
Abdeljalil D, Krichen M, Benhalima N, Benhadj N, Neji R.   +4 more
europepmc   +1 more source

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

Advanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang, Gaoge Sun, Xiangzheng Liu, Shuai Zuo, Pengyuan Wang, Boxiao Zhan, Zhi John Lu, Hang Yin, Ying Zhang   +8 more
wiley   +1 more source

Magnetic field sensing for 2D fault localization in underground power cables. [PDF]

PLoS One
Ali H, Qamar A, Alqahtani N, Alenezi AH, Ali F.   +4 more
europepmc   +1 more source

Fault Diagnosis and Location Method for Stator-Winding Single-Phase Grounding of Large Generator Based on Stepped-Frequency Pulse Injection. [PDF]

Sensors (Basel)
Lei B, Xu S, Liu Y, Zu W, Yu M, Guo Y, Dong L, Cheng Z.   +7 more
europepmc   +1 more source