Results 91 to 100 of about 239,493 (313)

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Expanding the clinical application of OPM-MEG using an effective automatic suppression method for the dental brace metal artifact

NeuroImage
Optically pumped magnetometer magnetoencephalography (OPM-MEG) holds significant promise for clinical functional brain imaging due to its superior spatiotemporal resolution.
Ruonan Wang, Kaiwen Fu, Ruochen Zhao, Dawei Wang, Zhimin Yang, Wei Bin, Yang Gao, Xiaolin Ning   +7 more
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

A conceptual and analytical approach to comparative analysis of country case studies: HIV and TB control programmes and health systems integration.

, 2010
Attempts to comparatively analyse large-scale communicable disease control programmes have, for the most part, neglected the wider health system contexts within which the programmes lie.
Atun, Rifat, J. W. Rudge, Shigayeva, Altynay, Mounier-Jack, Sandra, J. V. Lazarus, Naik, Neepa, R. Atun, Rudge, James W, Lazarus, Jeff, S. Mounier-Jack, Coker, Richard, R. Coker, N. Naik, J. Balen, Balen, Julie, Lazarus, Jeffrey V, A. Shigayeva   +16 more
core   +1 more source

An integrated magnetics component [PDF]

, 2013
The present invention relates to an integrated magnetics component comprising a magnetically permeable core comprising a base member extending in a horizontal plane and first, second, third and fourth legs protruding substantially perpendicularly from the base member.
Andersen, Michael A. E.; id_orcid 0000-0002-5612-0541, Ouyang, Ziwei; id_orcid 0000-0001-7046-9224, Zhang, Zhe; id_orcid 0000-0001-8407-3167   +2 more
openaire  

Immunomodulation of Patients with Canine Visceral Leishmaniasis at Different Stages: A 12-Month Follow-Up Study Using LaSap

Vaccines
Background/Objectives: Canine visceral leishmaniasis (CVL) is one of the main neglected protozoan diseases in the world. Dogs play a fundamental role in the maintenance of Leishmania infantum in the Americas, and we have already encountered resistance ...
Kelvinson Fernandes Viana, Adrieli Barboza de Souza, Sara Torres, Maria Camila Escobar Garcia, Açucena Veleh Rivas, Alex Sander Rodrigues Cangussu, Francisca Hildemagna Guedes da Silva, Rodolfo Cordeiro Giunchetti   +7 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Structural convergence and membrane interactions of Aβ1-42 along the primary nucleation process studied by solid state NMR

Communications Chemistry
Non-specific disruption of cellular membranes induced by amyloidogenic aggregation of β-amyloid (Aβ) peptides remains a viable cytotoxicity mechanism in Alzheimer’s disease (AD).
Maurine K. Kengwerere, June M. Kenyaga, Peng Xiao, Shubha S. Gunaga, Faith J. Scott, Xyomara Wutoh-Hughes, James Wang, Brian Lum, Yan Sun, Frederic Mentink-Vigier, Tuo Wang, Wei Qiang   +11 more
doaj   +1 more source

Source imaging method based on diagonal covariance bases and its applications to OPM-MEG

NeuroImage
Magnetoencephalography (MEG) is a noninvasive imaging technique used in neuroscience and clinical research. The source estimation of MEG involves solving a highly underdetermined inverse problem, which requires additional constraints to restrict the ...
Wen Li, Fuzhi Cao, Nan An, Wenli Wang, Chunhui Wang, Weinan Xu, Dexin Yu, Min Xiang, Xiaolin Ning   +8 more
doaj   +1 more source