Results 101 to 110 of about 778,766 (292)

Structural convergence and membrane interactions of Aβ1-42 along the primary nucleation process studied by solid state NMR

Communications Chemistry
Non-specific disruption of cellular membranes induced by amyloidogenic aggregation of β-amyloid (Aβ) peptides remains a viable cytotoxicity mechanism in Alzheimer’s disease (AD).
Maurine K. Kengwerere, June M. Kenyaga, Peng Xiao, Shubha S. Gunaga, Faith J. Scott, Xyomara Wutoh-Hughes, James Wang, Brian Lum, Yan Sun, Frederic Mentink-Vigier, Tuo Wang, Wei Qiang   +11 more
doaj   +1 more source

Source imaging method based on diagonal covariance bases and its applications to OPM-MEG

NeuroImage
Magnetoencephalography (MEG) is a noninvasive imaging technique used in neuroscience and clinical research. The source estimation of MEG involves solving a highly underdetermined inverse problem, which requires additional constraints to restrict the ...
Wen Li, Fuzhi Cao, Nan An, Wenli Wang, Chunhui Wang, Weinan Xu, Dexin Yu, Min Xiang, Xiaolin Ning   +8 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Artificial intelligence driven Mid-IR photoimaging device based on van der Waals heterojunctions of black phosphorus

Nanophotonics
Mid-infrared (Mid-IR) photodetection and imaging are pivotal across diverse applications, including remote sensing, communication, and spectral analysis.
Wang Ziqian, Wang Huide, Wang Chen, Bao Yushuo, Zheng Weiying, Weng Xiaoliang, Zhu Yihan, Liu Yi, Zhang Yule, Tian Xilin, Sun Shuo, Cao Rui, Shi Zhe, Chen Xing, Qiu Meng, Wang Hao, Liu Jun, Chen Shuqing, Zeng Yu-Jia, Liao Wugang, Huang Zhangcheng, Li Haiou, Gao Lingfeng, Li Jianqing, Fan Dianyuan, Zhang Han   +25 more
doaj   +1 more source

Optimizing DC-DC Converters through Interleaved Parallel Magnetic Integration: A Research Review

International Journal of Electrical, Energy and Power System Engineering
One of the main areas of focus for power electronics development nowadays is interleaved parallel magnetic integration technology. On the basis of introducing the staggered parallel connection technology of internal combustion engines and power systems ...
Muhammad Qasim Nawaz, Aimal Khan Khan
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Integration of High-Brightness QLED-Excited Diamond Magnetic Sensor

Micromachines
The nitrogen-vacancy (NV) center magnetic sensor, leveraging nitrogen-vacancy quantum effects, enables high-sensitivity magnetic field detection via optically detected magnetic resonance (ODMR).
Pengfei Zhao, Junjun Du, Jinyu Tai, Zhaoqi Shang, Xia Yuan, Yuanyuan Shi   +5 more
doaj   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source