Results 61 to 70 of about 4,700,178 (307)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
IEEE Open Journal of Power ElectronicsThe 48 V voltage regulation modules (VRM) for microprocessors feature a high voltage transformation ratio, large current, and ultra-low voltage output. The solutions based on high-turns-ratio transformers are the most popular ones.
Kangping Wang +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Machine learning reveals orbital interaction in materials
Science and Technology of Advanced Materials, 2017 We propose a novel representation of materials named an ‘orbital-field matrix (OFM)’, which is based on the distribution of valence shell electrons. We demonstrate that this new representation can be highly useful in mining material data.
Tien Lam Pham +6 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Stackless Onboard Coil for Dynamic Wireless Power Transfer
IEEE Open Journal of Power ElectronicsDynamic wireless power transfer (DWPT) technology is emerging as a key enabler for in-motion charging of electric vehicles (EVs), allowing continuous energy transfer without the need for dedicated charging stops.
Shuntaro Inoue +9 more
doaj +1 more source
The boundary integral method for magnetic billiards [PDF]
Journal of Physics A: Mathematical and General, 2000 28 pages, 12 ...
Hornberger, K., Smilansky, U.
openaire +3 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
A Comprehensive Study of Steady-State Modeling Techniques for Magnetic Coupling in DC/DC Converters
IEEE AccessMagnetic coupling is widely employed in multiphase interleaved DC/DC converters owing to its inherent advantages of current ripple reduction and DC flux cancellation.
Xiao Yu, Jens Friebe, Peter Zacharias
doaj +1 more source