Results 81 to 90 of about 4,700,178 (307)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Light-Triggered Graphene/Black Phosphorus Heterostructure FET Platform for Ultrasensitive Detection of Alzheimer’s Disease Biomarkers at the Zeptomole Level

Research
Due to the low concentration of amyloid-beta (Aβ) in plasma and the high content of interfering factors, the conventional detection method for the quantification of Aβ still faces the problem of insufficient limit of detection (LOD).
Huide Wang, Meng Qiu, Chen Wang, Liding Zhang, Ning Fan, Zhi Chen, Yi Liu, Tianzhong Li, Ziqian Wang, Yihan Zhu, Yule Zhang, Xilin Tian, Yun Wang, Mingmin Yang, Dianyuan Fan, Qingming Luo, Ke Jiang, Haiming Luo, Han Zhang   +18 more
doaj   +1 more source

Institute on Community Integration Annual Report: 2010-11

, 2011
The annual report summarizing the work and community impact of the Institute on Community Integration, a federally–designated University Center for Excellence in Developmental Disabilities working to improve community services and social supports for ...
Institute on Community Integration
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Beyond correlation: functional OPTO-MAgnetic Integration Concept (OPTOMAIC) to reveal the brain-wide signature of local neuronal signals-of-interest. [PDF]

Neurophotonics, 2022
Cleppien D, Aedo-Jury F, Stroh A.
europepmc   +1 more source

Institute on Community Integration Annual Report: 2009-10

, 2010
The annual report summarizing the work and community impact of the Institute on Community Integration, a federally–designated University Center for Excellence in Developmental Disabilities working to improve community services and social supports for ...
Institute on Community Integration
core  

Magnetic Maps of Indoor Environments for Precise Localization of Legged and Non-legged Locomotion [PDF]

, 2013
The magnetic field in indoor environments is rich in features and exceptionally easy to sense. In conjunction with any form of odometry, such as wheel- or IMUbased, a map of this field can be used to precisely localize a human or robot in indoor ...
Michael Lichtenstern, Brian J. Julian, Patrick Robertson, Frassl, Martin, Robertson, Patrick, Martin Frassl, Doniec, Marek, Michael Angermann, Marek Doniec, Angermann, Michael, Lichtenstern, Michael, Julian, Brian J.   +11 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Comparative evaluation of a deep learning method QNet and LCModel for MRS quantification on the cloud computing platform CloudBrain-MRS

BMC Medical Imaging
Objectives Reliable magnetic resonance (MR) spectroscopy (MRS) quantification is key to accurate clinical diagnosis. This study aimed to statistically compare the metabolite quantification of human brain MRS between the deep learning method QNet and the ...
Meijin Lin, Lin Guo, Dicheng Chen, Jianshu Chen, Zhangren Tu, Xu Huang, Jianhua Wang, Ji Qi, Yuan Long, Zhiguo Huang, Di Guo, Xiaobo Qu, Haiwei Han   +12 more
doaj   +1 more source

Formability and mechanism of ultra-thin titanium foil under the elevated temperature and high strain rate in electromagnetic forming

Journal of Materials Research and Technology
Electromagnetic forming (EMF) is a high-speed forming process with significant potential for manufacturing bipolar plates. However, titanium's low conductivity requires the use of a driver sheet in traditional EMF, limiting its formability improvement ...
Zelin Wu, Pengxin Dong, Yifan Huang, Yao Chen, Runze Liu, Quanliang Cao, Liang Li, Hao Wang, Xiaotao Han, Qiuliang Wang   +9 more
doaj   +1 more source