Results 61 to 70 of about 1,852,770 (211)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Nanocomposites comprised of homogeneously dispersed magnetic iron-oxide nanoparticles and poly(methyl methacrylate)

Beilstein Journal of Nanotechnology, 2018
Nanocomposites with a high, uniform loading of magnetic nanoparticles are very desirable for applications such as electromagnetic shielding and cancer treatment based on magnetically induced hyperthermia.
Sašo Gyergyek, David Pahovnik, Ema Žagar, Alenka Mertelj, Rok Kostanjšek, Miloš Beković, Marko Jagodič, Heinrich Hofmann, Darko Makovec   +8 more
doaj   +1 more source

Tailoring Fe/Ag Superparamagnetic Composites by Multilayer Deposition

, 2005
The magnetic properties of Fe/Ag granular multilayers were examined by SQUID magnetization and Mossbauer spectroscopy measurements. Very thin (0.2 nm) discontinuous Fe layers show superparamagnetic properties that can be tailored by the thickness of both
C. Van Haesendonck, D. Kaptás, Dormann J. L., E. Szilágyi, J. Balogh, J. Swerts, K. Temst, L. F. Kiss, S. Vandezande, T. Pusztai, Á. Tunyogi   +10 more
core   +1 more source

Orbital order and ferrimagnetic properties of the new compound $Sr_8 Ca Re_3 Cu_4 O_{24}$ [PDF]

, 2004
By means of the LSDA+U method and the Green function method, we investigate the electronic and magnetic properties of the new material of Sr$_8$CaRe$_3$Cu$_4$O$_{24}$.
I. Yamada, J. Kanamori, J. G. Bednorz, Masanori Kohno, N. N. Bogolyubov, N. N. Bogolyubov, P. Blaha, S. Jin, S. V. Tyablikov, W. Marshall, Xiangang Wan, Xiao Hu   +11 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Ferromagnet-Superconductor Hybrids

, 2004
A new class of phenomena discussed in this review is based on interaction between spatially separated, but closely located ferromagnets and superconductors. They are called Ferromagnet-Superconductor Hybrids (FSH).
Lyuksyutov, I. F., Pokrovsky, V. L.
core   +1 more source

Structural and magnetic properties of Pr-alloyed MnBi nanostructures [PDF]

, 2013
The structural and magnetic properties of Pr-alloyed MnBi (short MnBi-Pr) nanostructures with a range of Pr concentrations have been investigated. The nanostructures include thin films having Pr concentrations 0, 2, 3, 5 and 9 atomic percent and melt ...
Kharel, P., Li, X. Z., Sellmyer, D. J., Shah, V. R., Shield, J. E., Skomski, R., Zhang, W. Y.   +6 more
core   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Acoustic and magnetic properties of magnetic fluids

Archives of Acoustics, 2014
The influence of magnetic field on the acoustic and magnetic properties of magnetic liquids is discussed. By fitting the curve of Taketomi's theory to the experimental data of the anisotropy of ultrasonic attenuation, the values of quantities describing ...
A. SKUMIEL, T. HORNOWSKI, A. JÓZEFCZAK
doaj