Results 101 to 110 of about 8,638 (296)

Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis

Advanced Science, EarlyView.
This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou, Jing Luan, Xiaoyong Xu, Jianhua Qin, Shuang Ma, Jiyuan He, Na Sun, Wei Zhang, Minghui Gao   +8 more
wiley   +1 more source

Microwave Ultrafast Heating on Iron‐based Nanogap Catalysts for CO2 Reduction Coupling with Coke Removal

Advanced Science, EarlyView.
This study employs a nanogap‐induced microwave discharge strategy to pretreat coke deposits on iron‐based catalysts with engineered nanogaps, causing ultrarapid heating to 1990 K within seconds, selectively eliminating >70% surface carbon deposits and converting waste plastics and greenhouse gases into syngas.
Xi Shen, Zhenyu Zhao, Jinsong Zhang, Hong Li, Xin Gao   +4 more
wiley   +1 more source

Intube two-phase flow probabilities based on capacitance signal clustering [PDF]

, 2009
To study the objectivity in flow pattern mapping of horizontal two-phase flow in macroscale tubes, a capacitance sensor is developed for use with refrigerants. Sensor signals are gathered with R410A in an 8mm I.D.
Canière, Hugo, De Paepe, Michel, T'Joen, Christophe   +2 more
core   +1 more source

Investigation on a complex type of magnetic refrigerants for the Ericsson magnetic refrigeration.

TEION KOGAKU (Journal of Cryogenics and Superconductivity Society of Japan), 1986
A complex type of magnetic refrigerant for the Ericsson cycle has been investigated. For the magnetic refrigerant in the temperature range above -15K we have to use the ferromagnetic material, which has the internal magnetic field to arrange its spin system as far as using a magnetic field of -6T, because of increasing of the thermal excitation energy ...
Takasu HASHIMOTO, Tohru KUZUHARA, Masashi SAHASHI, Koichiro INOMATA, Akihisa TOMOKIYO, Hideki YAYAMA   +5 more
openaire   +2 more sources

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

Advanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang, Zhen Wang, Shuang Li, Chao Luo, Han Li, Shengjie Ma, Pai Wang, Heshi Liu, Lijun Sun, Yue Yin, Weizhen Zhang, Quan Wang   +11 more
wiley   +1 more source

Quantum degenerate mixtures of strontium and rubidium atoms

, 2013
We report on the realization of quantum degenerate gas mixtures of the alkaline-earth element strontium with the alkali element rubidium. A key ingredient of our scheme is sympathetic cooling of Rb by Sr atoms that are continuously laser cooled on a ...
Bayerle, Alex, Grimm, Rudolf, Parigger, Mark, Pasquiou, Benjamin, Schreck, Florian, Stellmer, Simon, Szczepkowski, Jacek, Tzanova, Slava   +7 more
core   +1 more source

An All‐Soft Wearable Electrochemiluminescence Chip for Sweat Metabolite Detection

Advanced Science, EarlyView.
A wearable electrochemiluminescence chip for sweat metabolite monitoring is pioneered, integrating “all‐soft” components: a flexible closed bipolar electrode (c‐BPE) array based on laser‐induced graphene (LIG), a laser‐cut microfluidic layer for sweat collection, and deep eutectic solvents (DES)‐based conductive ionogels for ECL emission.
Wei Nie, Jie Jiang, Xi Wei, Linfeng Zhuo, Danyang Li, Mingyu Jia, Tianhua Zheng, Hua Cui   +7 more
wiley   +1 more source

Stable superconducting magnet [PDF]

, 1967
Operation of a superconducting magnet is considered. A method is described for; (1) obtaining a relatively high current in a superconducting magnet positioned in a bath of a gas refrigerant; (2) operating a superconducting magnet at a relatively high ...
Boom, R. W.
core   +1 more source

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

A CF3I-based SDD Prototype for Spin-independent Dark Matter Searches

, 2008
The application of Superheated Droplet Detectors (SDDs) to dark matter searches has so far been confined to the light nuclei refrigerants C2ClF5 and C4F10 (SIMPLE and PICASSO, respectively), with a principle sensitivity to spin-dependent interactions ...
Collaboration, Simple, Felizardo, M., Girard, T. A., Giuliani, F., Limagne, Denis, Marques, J. G., Martins, R. C., Miley, H. S., Morlat, T., Payne, R. F., Ramos, A. R., Waysand, G.   +11 more
core   +1 more source