Results 51 to 60 of about 13,097,269 (248)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Magnetic Resonance Image restoration [PDF]

Journal of Mathematical Imaging and Vision, 1995
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Stephen J. Garnier, Griff L. Bilbro, James W. Gault, Wesley E. Snyder   +3 more
openaire   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Bias Correction of Multiple MRI Images Based on an Improved Nonparametric Maximum Likelihood Method

IEEE Access, 2019
With the wide application of nuclear magnetic resonance imaging, the multiplicative bias field in nuclear magnetic resonance images has created great difficulties for doctors in reading diagnostics and for computers in autoprocessing.
Yan Xu, Shunbo Hu, Yuyue Du
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Therapeutic response of immunoglobulin 4-related aortitis and pancreatitis demonstrated by diffusion-weighted MRI

Radiology Case Reports, 2019
Immunoglobulin (IgG) 4-related disease is a systemic inflammatory disease, and it affects vascular system as aortitis, periaortitis, or aneurysm. However, due to a lack of serum biomarker on aortic damage and the multiorgan involvement, it is difficult ...
Shogo Doi, Yasuyoshi Kuroiwa, PhD, Kazunori Kusumoto, MD, Atsushi Yamashita, MD, PhD, Eiji Furukoji, MD, PhD, Hiroshi Tai, MD, Yasushi Kihara, MD, Toshinori Hirai, MD, PhD, Yujiro Asada, MD, PhD, Takuroh Imamura, MD, PhD   +9 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Periductal iron-corrected T1 is a predictor of adverse outcomes in large-duct primary sclerosing cholangitis

BMC Medical Imaging
Background Concentric periductal fibrosis, commonly referred to as “onion skin” fibrosis, is a histological hallmark of primary sclerosing cholangitis (PSC) and associated with the development of biliary-type cirrhosis and end-stage liver disease.
Emmanuel A. Selvaraj, Ahmed Ba-Ssalamah, Sarah Poetter-Lang, Bruno Paun, Gerard R. Ridgway, Cayden Beyer, Anneli Andersson, Sir Michael Brady, Michele Pansini, Emma L. Culver, Adam Bailey, Michael Pavlides DPhil   +11 more
doaj   +1 more source

Imaging Methods: Magnetic Resonance Imaging

Circulation: Cardiovascular Imaging, 2023
Myocardial inflammation occurs following activation of the cardiac immune system, producing characteristic changes in the myocardial tissue. Cardiovascular magnetic resonance is the non-invasive imaging gold standard for myocardial tissue characterization, and is able to detect image signal changes that may occur resulting from inflammation, including ...
Katharine E. Thomas, Anastasia Fotaki, René M. Botnar, Vanessa M. Ferreira   +3 more
openaire   +3 more sources