Results 61 to 70 of about 456,396 (268)

The problem of metal needles in acupuncture-fMRI studies [PDF]

, 2011
Acupuncture is a therapy based on sensory stimulation of the human body by means of metal needles. The exact underlying mechanisms of acupuncture have not been clarified so far. Functional magnetic resonance imaging (fMRI) has become an important tool
Beißner, Florian, Thomas Schockert, Schockert, Thomas, Florian Beissner, Ulrike Nöth, Nöth, Ulrike   +5 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Multimodal Medical Image Fusion of Positron Emission Tomography and Magnetic Resonance Imaging Using Generative Adversarial Networks

Behavioural Neurology, 2022
Multimodal medical image fusion is a current technique applied in the applications related to medical field to combine images from the same modality or different modalities to improve the visual content of the image to perform further operations like ...
R. Nandhini Abirami, P. M. Durai Raj Vincent, Kathiravan Srinivasan, K. Suresh Manic, Chuan-Yu Chang   +4 more
doaj   +1 more source

Use of Nuclear Magnetic Resonance Imaging Angiography to Follow-Up Arterial Remodeling in an Animal Model [PDF]

, 1998
Appropriately sized arteries in small animals may be possible models for studying the remodeling process as occurs after arterial balloon injury in humans. Magnetic resonance imaging (MRI) is able to noninvasively image tissue in vivo.
Schwaiger, Markus, Huehns, Tanya Y., Höfling, Berthold, Nekolla, Stephan, Nikol, Sigrid, Schirmer, Johannes, Esin, Serap   +6 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Image construction methods for phased array magnetic resonance imaging

, 2004
Purpose To study image construction in phased array magnetic resonance imaging (MRI) systems from a statistical signal processing point of view. Materials and Methods Three new approaches for image combination with multiple coils are proposed: 1) one ...
Larsson, Erik G.,, Erdogmus, Deniz,, Yan, Rui,, Fitzimmons, Jeffrey R.,, Principe, Jose C.,   +4 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Automated computer-assisted detection system for cerebral aneurysms in time-of-flight magnetic resonance angiography using fully convolutional network

BioMedical Engineering OnLine, 2020
Background As the rupture of cerebral aneurysm may lead to fatal results, early detection of unruptured aneurysms may save lives. At present, the contrast-unenhanced time-of-flight magnetic resonance angiography is one of the most commonly used methods ...
Geng Chen, Xia Wei, Huang Lei, Yang Liqin, Li Yuxin, Dai Yakang, Geng Daoying   +6 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

An image-computable model for the stimulus selectivity of gamma oscillations

eLife, 2019
Gamma oscillations in visual cortex have been hypothesized to be critical for perception, cognition, and information transfer. However, observations of these oscillations in visual cortex vary widely; some studies report little to no stimulus-induced ...
Dora Hermes, Natalia Petridou, Kendrick N Kay, Jonathan Winawer   +3 more
doaj   +1 more source