Results 31 to 40 of about 125,791 (264)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Finite Element Analysis of Magnetic Saturation of Disk-type Magnetorheological Brake

open access: yesJixie chuandong, 2016
An evaluation magnetic saturation rate is proposed due to magnetic saturation degree not clear in the magnetorheological device. The magnetic field finite element analysis of disc- type magnetorheological brake is carried out,and the simulation results ...
Qiao Zhen, Huang Jin
doaj  

New optical differential protection algorithm applied in bus protection

open access: yesThe Journal of Engineering, 2018
In order to improve the speed and reliability of bus protection, people put forward the optical current transformer (OCT) replaced the traditional electric–magnetic current transformer.
Zhu Sitong   +4 more
doaj   +1 more source

Design and Analysis of 15 MW SPM Vernier Generator for Direct-Drive Wind Turbine Applications

open access: yesEnergies, 2023
This paper presents the design and an analysis of a surface PM vernier generator (SPMVG) for MW-scale direct-drive (DD) wind turbine application. An SPMVG has the advantage of higher torque density; however, especially at higher power ratings with ...
Abdur Rehman, Byungtaek Kim
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Operation Characteristics of Adjustable Field IPMSM Utilizing Magnetic Saturation

open access: yesEnergies, 2021
This paper describes an interior permanent magnet synchronous motor (IPMSM) based on a new adjustable field method. The proposed PM motor achieved magnetic field control utilizing magnetic saturation.
Kiyohiro Iwama, Toshihiko Noguchi
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Review of Electromagnetic Vibration in Electrical Machines

open access: yesEnergies, 2018
Electrical machines are important devices that convert electric energy into mechanical work and are widely used in industry and people’s life. Undesired vibrations are harmful to their safe operation.
Xueping Xu, Qinkai Han, Fulei Chu
doaj   +1 more source

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