Results 91 to 100 of about 108,533 (297)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Intrinsic, multiplexable sensors for electric field strength using structural slow light in phase-shifted fibre Bragg gratings [PDF]

, 2012
In this paper we demonstrate through simulation the potential for phase-shifted fibre Bragg gratings incorporating structural slow light to enable intrinsic reflection-mode point sensors for electric field or voltage.
Philip Orr, Niewczas, Pawel, Paweł Niewczas, Orr, Philip   +3 more
core   +1 more source

Development of an Embedded Myokinetic Prosthetic Hand Controller

Sensors, 2019
The quest for an intuitive and physiologically appropriate human machine interface for the control of dexterous prostheses is far from being completed. In the last decade, much effort has been dedicated to explore innovative control strategies based on ...
Francesco Clemente, Valerio Ianniciello, Marta Gherardini, Christian Cipriani   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Magnetic Sensors for Biomedical Applications

, 2019
Magnetic Sensors for Biomedical Applications offers a comprehensive review of magnetic biosensor modelling and simulation. The authors—noted experts on the topic—explore the model's strengths and weaknesses and discuss the competencies of different ...
Nabaei, Vahid, Heidari, Hadi
core  

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

A novel inductive electromagnetic energy harvester for condition monitoring sensors

, 2010
As the operation of electrical power networks becomes increasingly sophisticated, the role of condition monitoring is expanding. The burden of implementing additional condition monitoring will be eased if self-powered, fully autonomous sensors can be ...
Fraser, Leigh, Judd, Martin, Roscoe, Nina   +2 more
core  

Dealing with Magnetic Disturbances in Human Motion Capture: A Survey of Techniques

Micromachines, 2016
Magnetic-Inertial Measurement Units (MIMUs) based on microelectromechanical (MEMS) technologies are widespread in contexts such as human motion tracking.
Gabriele Ligorio, Angelo Maria Sabatini
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Wireless Magnetic Sensor Network for Road Traffic Monitoring and Vehicle Classification

Transport and Telecommunication, 2016
Efficiency of transportation of people and goods is playing a vital role in economic growth. A key component for enabling effective planning of transportation networks is the deployment and operation of autonomous monitoring and traffic analysis tools ...
Velisavljevic Vladan, Cano Eduardo, Dyo Vladimir, Allen Ben   +3 more
doaj   +1 more source