Results 51 to 60 of about 798,637 (316)

Spiral structures in helicoidal magnets [PDF]

JETP Letters, 2012
Structure and properties of two-dimensional spiral textures in helical ferromagnets have been studied. In these magnetic mediums have been predicted new types of periodical structures - spiral lattices.
Borisov, A. B., Rybakov, F. N.
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Coupling between Spin and Charge Order Driven by Magnetic Field in Triangular Ising System LuFe2O4+δ

Crystals, 2018
We present a study of the magnetic-field effect on spin correlations in the charge ordered triangular Ising system LuFe2O4+δ through single crystal neutron diffraction.
Lei Ding, Fabio Orlandi, Dmitry D. Khalyavin, Andrew T. Boothroyd, Dharmalingam Prabhakaran, Geetha Balakrishnan, Pascal Manuel   +6 more
doaj   +1 more source

Water-oriented magnetic anisotropy transition

Nature Communications, 2021
Little is known about how the orientation of coordinated water molecules affects the magnetic properties of single molecule magnets. Here the authors combine experimental data and theoretical calculations to study how the rotation of water molecules ...
Sheng-Qun Su, Shu-Qi Wu, Masato Hagihala, Ping Miao, Zhijian Tan, Shuki Torii, Takashi Kamiyama, Tongtong Xiao, Zhenxing Wang, Zhongwen Ouyang, Yuji Miyazaki, Motohiro Nakano, Takumi Nakanishi, Jun-Qiu Li, Shinji Kanegawa, Osamu Sato   +15 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

NMR screening of low molecular weight inhibitors targeting the papain‐like protease (PLPro) of SARS‐CoV‐2

FEBS Open Bio
The Papain‐like protease (PLPro) from SARS‐CoV‐2 plays an important role in the cleavage of the polyproteins Pp1a and Pp1ab as well as in the suppression of the immune response by deISG15ylation. Considerable effort is therefore devoted to developing low
Dennis J. Pyper, Sridhar Sreeramulu, Benjamin T. Lanham, Elizabeth M. Engle, David Fushman, Harald Schwalbe   +5 more
doaj   +1 more source

Simulating Magnetic Ordering and Exchange Interactions in Ni₂Co(BO₃)₂

Physics
First-principles calculations of the structural and magnetic properties of kotoite Ni2Co(BO3)2 are carried out. The minimization of the lattice parameters shows the values to be in good agreement with the experimental data (the difference is less than 1%)
Svetlana Sofronova, Artem Chernyshev, Anna Selyanina, Aleksandr Krylov, Timofey Tislenko   +4 more
doaj   +1 more source

Magnetic structure driven by monoclinic distortions in the double perovskite Sr2YRuO6

New Journal of Physics, 2015
The monoclinic double perovskite Sr _2 YRuO _6 has recently gained a renewed interest in order to get a deeper insight into the exotic magnetic ground states associated with geometric frustration.
P L Bernardo, L Ghivelder, H S Amorim, J J Neumeier, S García   +4 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source