Results 61 to 70 of about 798,637 (316)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Magnetic properties and magnetic domain structure of bulk glass forming Nd60Al10Fe20Co10 alloy

, 2004
The transition from hard to soft magnetic behaviour with increasing quenching rate is shown for Nd60WAl10Fe20Co10 melt-spun ribbons with different thickness.
Eckert J, Loser W, 李维火, 魏炳忱, 喻更生, Roth S, Wei, BC (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100080, Peoples R China.   +6 more
core   +1 more source

Ferrimagnetic Structure of 3C Pyrrhotite (Fe7S8) From Neutron Diffraction

Geochemistry, Geophysics, Geosystems
Pyrrhotite is a paleomagnetically important magnetic mineral in many geological settings. It forms numerous polytypes with different stacking patterns of the NiAs structure along the crystallographic c axis to produce different vacancy‐ordered ...
Chin‐Wei Wang, Chorng‐Shern Horng, Andrew P. Roberts   +2 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Oscillating magnetic field disrupts magnetic orientation in Zebra finches, Taeniopygia guttata

, 2009
Background Zebra finches can be trained to use the geomagnetic field as a directional cue for short distance orientation. The physical mechanisms underlying the primary processes of magnetoreception are, however, largely unknown.
Wiltschko, Wolfgang, Voss Joe, Tim Ruploh, Ruploh, Tim, Nina Keary, Wolfgang Wiltschko, Keary, Nina, Thalau, Peter, Wiltschko, Roswitha, Ruploh Tim, Voss, Joe, Wiltschko, Wolfgang (Prof. Dr.), Joe Voss, Roswitha Wiltschko, Peter Thalau, Wiltschko Roswitha, Bischof Hans-Joachim, Thalau Peter, Wiltschko Wolfgang, Keary Nina, Hans-Joachim Bischof, Bischof, Hans-Joachim   +21 more
core   +1 more source

A New Structure for the Magnetic Gear [PDF]

IEEE Access, 2019
In this paper, a new structure for increasing the magnetic gear torque is proposed, which has high torque density and high mechanical properties. The permanent magnets (PMs) of the outer rotor are spoked and magnetized along the tangential direction. The PMs of inner rotor are the surface-mount type and magnetized in the radial direction.
Libing Jing, Jun Gong, Zhangxian Huang, Tong Ben, Yuehua Huang   +4 more
openaire   +2 more sources

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Magnetic phase transitions in Gd64Sc36 studied using non-contact ultrasonics [PDF]

, 2013
The speed and attenuation of ultrasound propagation can be used to determine material properties and identify phase transitions. Standard ultrasonic contact techniques are not always convenient due to the necessity of using couplant; however, recently ...
Edwards, R. S. (Rachel Sian), Perry, R. (Robert), Trushkevych, Oksana, Fan, Yichao   +3 more
core   +1 more source