Results 191 to 200 of about 170,697 (259)

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan   +10 more
wiley   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin   +16 more
wiley   +1 more source

Magnetic susceptibility in the assessment of toxic heavy metal elements in the surface sediments of Inner Ambon Bay, Maluku province, Indonesia. [PDF]

open access: yesHeliyon
Noya Y   +8 more
europepmc   +1 more source

4f-Orbital mixing increases the magnetic susceptibility of Cp'3Eu. [PDF]

open access: yesChem Sci
Gunther SO   +14 more
europepmc   +1 more source

Normative trajectories of R 1 , R 2 * and magnetic susceptibility in basal ganglia on healthy ageing

open access: yes
Chan K   +6 more
europepmc   +1 more source

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