Results 101 to 110 of about 30,016 (261)
Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract
Advanced Robotics Research, EarlyView.We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis +7 more
wiley +1 more source
eLife, 2019 Bacillus subtilis ParB forms multimeric networks involving non-specific DNA binding leading to DNA condensation. Previously, we found that an excess of the free C-terminal domain (CTD) of ParB impeded DNA condensation or promoted decondensation of pre ...
Julene Madariaga-Marcos +4 more
doaj +1 more source
Single molecule thermodynamics of ATP synthesis by F$_1$-ATPase
, 2015 F$_\mathrm{o}$F$_1$-ATP synthase is a factory for synthesizing ATP in virtually all cells. Its core machinery is the subcomplex F$_1$-motor (F$_1$-ATPase) and performs the reversible mechanochemical coupling. Isolated F$_1$-motor hydrolyzes ATP, which is
Muneyuki, Eiro, Toyabe, Shoichi
core +1 more source
Waveguide Photoactuators: Materials, Fabrication, and Applications
Advanced Robotics Research, EarlyView.Waveguide photoactuators convert guided light into mechanical motion. Their tethered‐flexible design enables minimally invasive surgery and confined‐space robotics. This review aims to guide materials selection, device design, and system integration, accelerating the transition of waveguide photoactuators from laboratory prototypes to versatile ...
Minjie Xi +4 more
wiley +1 more source
, 2016 Controlling the transport, trapping, and filtering of nanoparticles is important for many applications. By virtue of their weak response to gravity and their thermal motion, various physical mechanisms can be exploited for such operations on ...
Alaee, Rasoul +3 more
core +1 more source
Advanced Science, EarlyView.This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva +28 more
wiley +1 more source
Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy
Advanced Science, EarlyView.This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao +6 more
wiley +1 more source
Magnetic Recording of Superconducting States
Metals, 2019 Local polarization of magnetic materials has become a well-known and widely used method for storing binary information. Numerous applications in our daily life such as credit cards, computer hard drives, and the popular magnetic drawing board toy, rely ...
Gorky Shaw +10 more
doaj +1 more source
Quadrupole Interaction of Non-diffracting Beams with Two-Level Atoms
, 2019 Recently it has been shown that the quadrupole interactions can be improved significantly as the atom interacts at near resonance with the Laguerre-Gaussian (LG) mode.
Al-Awfi, Saud, Bougouffa, Smail
core +1 more source
An Opto‐Actuated Hydrogel for Cell Mechanoactuation and Real‐Time Force Monitoring
Advanced Science, EarlyView.Researchers developed a mechanoactuated hydrogel interface where nanomachines exert forces on adhesion receptors and allow monitoring of traction force responses in real time. They demonstrate reversible talin recruitment, enhanced F‐actin polymerization, and a reduction in cell traction force when force is locally applied to focal adhesions of ...
Rinku Kumar +6 more
wiley +1 more source