Results 211 to 220 of about 30,016 (261)
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High-Resolution Single-Molecule Magnetic Tweezers
Annual Review of Biochemistry, 2022Single-molecule magnetic tweezers deliver magnetic force and torque to single target molecules, permitting the study of dynamic changes in biomolecular structures and their interactions. Because the magnetic tweezer setups can generate magnetic fields that vary slowly over tens of millimeters—far larger than the nanometer scale of the single molecule ...
Hyun-Kyu, Choi +3 more
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Recent Advances in Magnetic Tweezers
Annual Review of Biophysics, 2012Since their first demonstration of manipulation and mechanical coiling of a single DNA molecule, magnetic tweezers have become a popular and widely used single-molecule manipulation technique. Magnetic tweezers have yielded a wealth of information on the elastic properties of (coiled) DNA and have provided critical insights into the dynamic activity ...
Iwijn De Vlaminck, Cees Dekker
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New approaches in the design of magnetic tweezers–current magnetic tweezers
Journal of Magnetism and Magnetic Materials, 2016Abstract The main advantages of the magnetic tweezers are the low price and simplicity of use. However the range of their application is reduced due to shortcomings like, for example, the remanent induction of the core and interaction between ferromagnetic cores.
Valentina Bessalova +2 more
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Magnetic Tweezers with Magnetic Thin Films
Japanese Journal of Applied Physics, 2011Magnetic tweezers consisting of a 75×0.65×0.3 µm3 silicon oxide cantilever and a 72×13×0.3 µm3 silicon oxide plate deposited with magnetic thin films are fabricated and placed under various magnetic fields to observe their flexure. The principle of the magnetic tweezers is magnetic torque on condition that the high shape magnetic anisotropy is ...
Yi-Ping Hsieh, Zung-Hang Wei
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Exploring Condensins with Magnetic Tweezers
2017The signature activity of condensins as DNA reshaping machines is their ability to impose the giant loop architecture onto the chromosome. At the heart of this activity lies the propensity of the proteins to assemble into macromolecular clusters that bring distant DNA segments together.
Rupa, Sarkar, Valentin V, Rybenkov
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Magnetic Tweezers in Cell Biology
2007We discuss herein the theory as well as some design considerations of magnetic tweezers. This method of generating force on magnetic particles bound to biological entities is shown to have a number of advantages over other techniques: forces are exerted in noncontact mode, they can be large in magnitude (order of 10 nanonewtons), and adjustable in ...
Monica, Tanase +2 more
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Biofunctional Magnetic Tweezers
Science, 2001MATERIALS SCIENCE The viscoelastic properties of cells and intracellular transport forces have been studied with micrometer-sized transducers that can handle relatively large forces (tens of nanonewtons). Abdelghani-Jacquin et al. have made magnetic cobalt and iron particles more cell-friendly by plating them with gold in a spontaneous electrodeless ...
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Magnetically actuated micromechanical tweezers
Sensors and Actuators A: Physical, 2011Abstract Two planar actuators with magnetic thin films are used for magnetic tweezers. The planar actuators consisting of a pair of a 75 × 0.8 × 0.3 μm 3 silicon oxide beam and a 72 × 13 × 0.3 μm 3 silicon oxide plate deposited with a 65 × 4 × 0.1 μm 3 Ni magnetic thin film are successfully fabricated and successfully gripped to a single NPC-tw01 ...
Yi-Ping Hsieh +3 more
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Magnetic tweezers principles and promises
Magnetic tweezers have become popular with the outbreak of single molecule micromanipulation: catching a single molecule of DNA, RNA or a single protein and applying mechanical constrains using micron-size magnetic beads and magnets turn out to be easy. Various factors have made this possible: the fact that manufacturers have been preparing these beadsVincent, Croquette +3 more
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Magnetic tweezers for DNA micromanipulation
Review of Scientific Instruments, 2000We detail the design of an electromagnetic assembly capable of generating a constant magnetic field superimposed to a large magnetic field gradient (between 40 and 100 T/m), which was uniform over a large gap (between 1.5 and 2 cm). Large gaps allowed the use of wide high numerical-aperture lenses to track microspheres attached to DNA molecules with an
Charbel Haber, Denis Wirtz
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