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Biofunctional Magnetic Tweezers

Science, 2001
MATERIALS SCIENCE The viscoelastic properties of cells and intracellular transport forces have been studied with micrometer-sized transducers that can handle relatively large forces (tens of nanonewtons). Abdelghani-Jacquin et al. have made magnetic cobalt and iron particles more cell-friendly by plating them with gold in a spontaneous electrodeless ...
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Magnetic Tweezers for Single-Molecule Manipulation

2011
Magnetic tweezers provide a versatile tool enabling the application of force and torque on individual biomolecules. Magnetic tweezers are uniquely suited to the study of DNA topology and protein-DNA interactions that modify DNA topology. Perhaps due to its presumed simplicity, magnetic tweezers instrumentation has been described in less detail than ...
Yeonee, Seol, Keir C, Neuman
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Applications of Magnetic Tweezers to Studies of NAPs

2017
Nucleoid-associated proteins (NAPs) are important factors in shaping bacterial nucleoid and regulating global gene expression. A great deal of insights into NAPs can be obtained through studies using single DNA molecule, which has been made possible owing to recent rapid development of single-DNA manipulation techniques.
Ricksen S, Winardhi, Jie, Yan
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Magnetic Tweezers for Single-Molecule Experiments

2009
Over the last decade, single-molecule techniques have proven their wide applicability in the study of processive motor proteins and other enzymes, yielding insight into their kinetics and mechanochemistry. In the context of force spectroscopy of protein–nucleic acid interactions, optical tweezers, magnetic tweezers, and atomic force microscopy have ...
Vilfan, I. D.   +4 more
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Magnetically actuated micromechanical tweezers

Sensors and Actuators A: Physical, 2011
Abstract Two planar actuators with magnetic thin films are used for magnetic tweezers. The planar actuators consisting of a pair of a 75 × 0.8 × 0.3 μm 3 silicon oxide beam and a 72 × 13 × 0.3 μm 3 silicon oxide plate deposited with a 65 × 4 × 0.1 μm 3 Ni magnetic thin film are successfully fabricated and successfully gripped to a single NPC-tw01 ...
Yi-Ping Hsieh   +3 more
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Magnetic tweezers for DNA micromanipulation

Review of Scientific Instruments, 2000
We detail the design of an electromagnetic assembly capable of generating a constant magnetic field superimposed to a large magnetic field gradient (between 40 and 100 T/m), which was uniform over a large gap (between 1.5 and 2 cm). Large gaps allowed the use of wide high numerical-aperture lenses to track microspheres attached to DNA molecules with an
Charbel Haber, Denis Wirtz
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Particles sorting in micro-channel system utilizing magnetic tweezers and optical tweezers

2011 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, 2011
This is a research on classifying magnetic micro-particles in a micro flow tunnel, using an embedded inverted-laser tweezers system, a micro-flow pump and a micro-magnet. Manipulation of the particles in the micro-flow tunnel was achieved. An image recognition system integrated in the micro-flow tunnel was used to identify, count and separate different
Yung-Chiang Chung   +4 more
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Intracellular manipulation and measurement with multipole magnetic tweezers

Science Robotics, 2019
A platform technology for magnetic manipulation and measurement substantially improves intracellular navigation and characterization.
Xian Wang 0001   +11 more
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Magnetic tweezers in cell mechanics

The chapter provides an overview of the applications of magnetic tweezers in living cells. It discusses the advantages and disadvantages of magnetic tweezers technology with a focus on individual magnetic tweezers configurations, such as electromagnetic tweezers. Solutions to the disadvantages identified are also outlined. The specific role of magnetic
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Single-molecule covalent magnetic tweezers

Trends in Biochemical Sciences, 2023
Soham Chakraborty, Shubhasis Haldar
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