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New approaches in the design of magnetic tweezers–current magnetic tweezers
Journal of Magnetism and Magnetic Materials, 2016Abstract The main advantages of the magnetic tweezers are the low price and simplicity of use. However the range of their application is reduced due to shortcomings like, for example, the remanent induction of the core and interaction between ferromagnetic cores.
Valeria Rodionova, Nikolai Perov
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Controlled patterning of magnetic hydrogel microfibers under magnetic tweezers
2013 IEEE/RSJ International Conference on Intelligent Robots and Systems, 2013 3D tailor-made biodegradable scaffold integrated with biological cells or molecules is of great importance for tissue engineering. This paper addresses an improved method for exploring magnetic tweezers in patterning and aligning magnetic hydrogel fiber to fabricate large-scale engineered cell-hydrogel constructs.
Chengzhi Hu +6 more
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Exploring Condensins with Magnetic Tweezers
2017The signature activity of condensins as DNA reshaping machines is their ability to impose the giant loop architecture onto the chromosome. At the heart of this activity lies the propensity of the proteins to assemble into macromolecular clusters that bring distant DNA segments together.
Rupa, Sarkar, Valentin V, Rybenkov
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Highly Parallel Magnetic Tweezers by Targeted DNA Tethering
Nano Letters, 2011 Single-molecule force-spectroscopy methods such as magnetic and optical tweezers have emerged as powerful tools for the detailed study of biomechanical aspects of DNA-enzyme interactions.
Iwijn de Vlaminck +2 more
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Magnetic Tweezers in Cell Biology
2007We discuss herein the theory as well as some design considerations of magnetic tweezers. This method of generating force on magnetic particles bound to biological entities is shown to have a number of advantages over other techniques: forces are exerted in noncontact mode, they can be large in magnitude (order of 10 nanonewtons), and adjustable in ...
Monica, Tanase +2 more
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Soft magnetic tweezers: A proof of principle
Review of Scientific Instruments, 2011We present here the principle of soft magnetic tweezers which improve the traditional magnetic tweezers allowing the simultaneous application and measurement of an arbitrary torque to a deoxyribonucleic acid (DNA) molecule. They take advantage of a nonlinear coupling regime that appears when a fast rotating magnetic field is applied to a ...
Francesco, Mosconi +2 more
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Magnetic nanowire-enhanced optomagnetic tweezers
2009 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, 2008We report an optomagnetic tweezers technique that utilizes the highly localized magnetic field gradients induced near the tip of a magnetic nanowire to provide strong trapping forces on magnetic nanoparticles with high spatial resolution. Integral to our approach is a method to trap, translate, and rotate a single magnetic nanowire in three dimensions.
Karan Kartik Mehta +2 more
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Particles sorting in micro-channel using magnetic tweezers and optical tweezers
The 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS), 2014This study evaluates a method for separating magnetic microparticles in a micro channel by using embedded inverted-laser tweezers, a microflow pump, and a micro magnet. Various particles were separated using optical and/or magnetic tweezers, and were identified and counted to determine the dependence of the sorting rate on the channel flow velocity ...
Yung-Chiang Chung +3 more
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Probing Chromatin Structure with Magnetic Tweezers
2018Magnetic tweezers form a unique tool to study the topology and mechanical properties of chromatin fibers. Chromatin is a complex of DNA and proteins that folds the DNA in such a way that meter-long stretches of DNA fit into the micron-sized cell nucleus.
Artur, Kaczmarczyk +4 more
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Magnetic tweezers principles and promises
Magnetic tweezers have become popular with the outbreak of single molecule micromanipulation: catching a single molecule of DNA, RNA or a single protein and applying mechanical constrains using micron-size magnetic beads and magnets turn out to be easy. Various factors have made this possible: the fact that manufacturers have been preparing these beadsVincent, Croquette +3 more
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