Results 51 to 60 of about 36,186 (269)
Pediatric Blood &Cancer, EarlyView.ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz +7 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Transactions of Nonferrous Metals Society of China, 2009 During the process of directional solidification, laser remelting/solidification in the layer on sintered magnets, die-upsetting of cast magnets, or die-upsetting of nano-composites, the arrangements of the easy-magnetization-axes of the hard magnetic phases (Nd2Fe14B, SmCo5 or Sm2Co17 type) in their designed directions have been studied. In Fe-Pt nano-
Xin-cai LIU, Ren XIE, Jing PAN
openaire +1 more source
Resilience of LTE-A/5G-NR Links Against Transient Electromagnetic Interference
MagnetismThis paper presents a comparative analysis of a long-term evolution advanced (LTE-A) and fifth-generation new radio (5G-NR), focusing on the effects of transient electromagnetic interference (EMI) caused by catenary–pantograph contact in a railway ...
Sharzeel Saleem, Mir Lodro
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Magnetization transfer in magnetic resonance fingerprinting
Magnetic Resonance in Medicine, 2019 PurposeTo study the effects of magnetization transfer (MT, in which a semi‐solid spin pool interacts with the free pool), in the context of magnetic resonance fingerprinting (MRF).MethodsSimulations and phantom experiments were performed to study the impact of MT on the MRF signal and its potential influence on T1 and T2 estimation.
Tom Hilbert +7 more
openaire +8 more sources
MagnetismWe report our numerical results on the stability of the skyrmion crystal phase in an external magnetic field for both in-plane and out-of-plane directions in a centrosymmetric host. We analyze a spin model with the two-spin symmetric anisotropic exchange
Satoru Hayami
doaj +1 more source
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source