Results 61 to 70 of about 3,164,544 (309)

Entropy production in systems with long range interactions

, 2017
On a fine grained scale the Gibbs entropy of an isolated system remains constant throughout its dynamical evolution. This is a consequence of Liouville's theorem for Hamiltonian systems and appears to contradict the second law of thermodynamics.
Levin, Yan, Pakter, Renato
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Electrostatic Shock Structures in a Magnetized Plasma Having Non-Thermal Particles

Gases, 2022
A rigorous theoretical investigation has been made on the nonlinear propagation of dust-ion-acoustic shock waves in a multi-component magnetized pair-ion plasma (PIP) having inertial warm positive and negative ions, inertialess non-thermal electrons and ...
Sharmin Jahan, Subrata Banik, Nure Alam Chowdhury, Abdul Mannan, A A Mamun   +4 more
doaj   +1 more source

Magnetized strongly coupled plasmas and how to realize them in a dusty plasma setup

, 2012
Strongly coupled plasmas in which the interaction energy exceeds the kinetic energy play an important role in many astrophysical and laboratory systems including compact stars, laser plasmas and dusty plasmas.
Bonitz, M., Kählert, H., Löwen, H., Ott, T.   +3 more
core   +1 more source

On heat transfer in the presence of nano-sized particles suspended in a magnetized rotatory flow field

Case Studies in Thermal Engineering, 2019
In this paper, the rotatory non-Newtonian fluid flow subject to rigid disk is debated. The Casson fluid is used as a non-Newtonian fluid model and the fluid is equipped above the rigid disk.
K. Rehman, Iqra Shahzadi, M. Malik, Q. Al‐Mdallal, M. Zahri   +4 more
semanticscholar   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Research on the influencing factors of collision and infiltration of fine coal dust by magnetized charged droplets

Meikuang Anquan
Magnetized charging technology, as a new type of coupling enhanced dust reduction technology, can effectively improve the poor efficiency of traditional wet water mist in capturing fine and difficult to infiltrate coal dust. This study adopts theoretical
Hongjie ZHANG, Yuming ZHAO, Jiezhong WU, Shaocheng GE   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Effect of a Weak Electromagnetic Field on Particle Acceleration by a Rotating Black Hole

, 2012
We study high energy charged particle collisions near the horizon in an electromagnetic field around a rotating black hole and reveal the condition of the fine-tuning to obtain arbitrarily large center-of-mass (CM) energy.
Masashi Kimura, O. B. Zaslavskii, Takahisa Igata, Tomohiro Harada   +3 more
core   +1 more source