Results 61 to 70 of about 197,641 (308)

Modulation of the TGF‐β/Smad Signaling Pathway by a Bioactive Oxidized Polygonati Rhizoma Polysaccharide Crosslinked Chitosan Hydrogel as Therapeutic Carrier for Parkinson's Disease Treatment

open access: yesAdvanced Science, EarlyView.
An injectable, self‐healing COPRP hydrogel integrates structurally defined oxidized Polygonati rhizoma polysaccharide with carboxymethyl chitosan through dynamic Schiff‐base crosslinking. The bioactive matrix scavenges reactive oxygen species, suppresses neuroinflammation, protects dopaminergic neurons, and supports sustained levodopa release.
Peng Dai   +10 more
wiley   +1 more source

A jászóvári premontrei kanonokrend szerzetesrendi nevei az 1802-es visszaállítást követő évszázadban [Monastic names in the Premonstratensian Order at Jászóvár in the century following the 1802 restitution of the Order]

open access: yesNévtani Értesítő, 2014
This paper presents the names adopted by monks of the (canonical) Premonstratensian Order at Jászóvár during the 19th century, after the 1802 restitution of the Order.
Gasparics, Gyula
doaj  

A Hepatocyte‐to‐Stellate Cell Axis Couples Alternate‐Day Fasting to Liver Fibrosis Resolution via ATG7 S‐Nitrosylation

open access: yesAdvanced Science, EarlyView.
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang   +17 more
wiley   +1 more source

A Kiss Lajos-díj 2016. évi nyertese: dr. Póczos Rita [Winner of the 2016 Lajos Kiss Prize: Dr Rita Póczos]

open access: yesNévtani Értesítő, 2016
The Lajos Kiss Prize, awarded every two or three years since 2006, is considered to be a highly prestigious award for young onomasticians. The 2016 winner of the prize is Dr Rita Póczos, senior lecturer at the Department of Hungarian Linguistics of the ...
Hoffmann, István
doaj  

Integrated Multi‐Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC

open access: yesAdvanced Science, EarlyView.
Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Ning Zhang   +18 more
wiley   +1 more source

A személynevek fordítása Mikszáth Kálmán Szent Péter esernyője című regényének legújabb szlovák kiadásában [Examining personal names in the latest Slovakian translation of the novel entitled St. Peter’s Umbrella by Kálmán Mikszáth]

open access: yesNévtani Értesítő, 2015
The paper discusses the translatability and untranslatability of personal names in connection with the latest translation of the novel entitled St. Peter’s Umbrella by Kálmán Mikszáth.
Petovská, Flóra
doaj  

Nyelvhasználati sajátosságok a Szovjetunióhoz csatolt Kárpátalján a Vörös Zászló kerületi lap 1945–1946. évi anyagai alapján

open access: yesActa Academiae Beregsasiensis, Philologica
A sajtótermékek történelmi szempontú vizsgálata komoly hagyományokkal rendelkezik. Ezzel párhuzamosan a bennük megjelenő írások nyelvészeti szempontból is fontos források lehetnek.
Vilmos Gazdag
doaj   +1 more source

Shear‐Mode Direct Piezoelectric Response of Ferroelectric Nematic Liquid Crystals

open access: yesAdvanced Science, EarlyView.
Periodic shear‐induced electric current measurements are reported on two archetypic ferroelectric nematic liquid crystal compounds. From the temperature, frequency and shear angle dependent results of the first and second harmonic current signals together with temperature and oscillatory rheology measurements, the effective piezoelectric coupling ...
Péter Salamon   +4 more
wiley   +1 more source

CXCL3 Antagonism Reverses Systemic Antitumor Immune Memory Impairment Associated With High Tumor Burden and Sensitizes Anti‐PD‐1 Therapy

open access: yesAdvanced Science, EarlyView.
This study reveals that large tumors secrete more chemokine CXCL3, which recruits immunosuppressive neutrophils to the periphery, thereby impairing the activation and memory of systemic tumor‑reactive CD8+ T cells. CXCL3 antagonism restores systemic immune memory and enhances the antitumor efficacy of anti‑PD‑1 therapy, offering a potential strategy to
Ji Wang   +15 more
wiley   +1 more source

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