Results 71 to 80 of about 7,590,271 (296)

The Proof and Decryption of Goldbach Conjecture

open access: yesComputer Sciences & Mathematics Forum, 2023
In this paper, a few mathematical bases are given firstly. Then, the step thinness τp of primes is given as τp = Lo1 = P1ΠP/(P−1) for the inner character, having an lnX logarithmic outer character. The “best estimation and mutual exchange equivalent” are
Linfu Ge
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Half-linear Euler differential equation and its perturbations

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2016
We investigate oscillatory properties of perturbed half-linear Euler differential equation. We give an alternative proof (simpler and more straightforward) of the main result of [O. Došlý, H. Funková, Abstr. Appl. Anal. 2012, Art. ID 738472] and we prove
Ondrej Dosly
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Geometric main conjectures in function fields

open access: yesJournal für die reine und angewandte Mathematik (Crelles Journal)
Abstract We prove an equivariant main conjecture in Iwasawa theory along any rank-one, sign-normalized Drinfeld modular, split-at-∞ Iwasawa tower of a general function field of characteristic 𝑝, for the Iwasawa modules recently considered by Greither and Popescu in their proof of the classical equivariant main conjecture along the ...
Bley, Werner, Popescu, Cristian D.
openaire   +2 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

On locally irregular decompositions of subcubic graphs [PDF]

open access: yesOpuscula Mathematica, 2018
A graph \(G\) is locally irregular if every two adjacent vertices of \(G\) have different degrees. A locally irregular decomposition of \(G\) is a partition \(E_1,\dots,E_k\) of \(E(G)\) such that each \(G[E_i]\) is locally irregular.
Olivier Baudon   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

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