Results 171 to 180 of about 15,385,090 (308)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Essay on the role of the Debreceni Gyógyfürdő Kft.’s controlling system in the executive decision-making process

open access: yes, 2016
A dolgozatban bemutatásra kerül a controlling, valamint a controllingrendszer. Ehhez kapcsolódóan továbbá a modern vállalatirányításirendszer kialakulása is bemutatásra kerül. Mivel a dolgozat gyakorlati részében a Debreceni Gyógyfürdő Kft.
Kotosmann, Zoltán
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Stock controlling in a Hungarian company

open access: yes, 2017
A 21. század első évtizedeire a gazdasági élet minden területén beigazolódott és kiteljesedett a sokat hangoztatott megállapítás: „az információ hatalom”. Manapság szinte egyik piac sincs megkímélve a folytonos, olykor nagyon gyors változásoktól, és csak
Katona, Dávid
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Az üzleti intelligencia és az adattárházak controlling szemléletű bemutatása a National Instruments Hungary Kft. által

open access: yes, 2013
Dolgozatom első részében a controlling informatikai támogatásának újabb lehetőségeit mutatom be, ahol szemléltetem, hogy a controlling működéséhez egyre inkább elengedhetetlen az informatika alkalmazása.
Szalai, Anett
core  

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