Results 181 to 190 of about 15,385,090 (308)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Characteristics and main controlling factors for the development of shale micro pore-fracture in Tiemulike Formation, Yining Basin. [PDF]

Sci Rep
Feng Y, Ren Y, Sun W, Jiang T.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Greenhouse Gas Emissions during Oil Shale Crushing and Its Main Controlling Factors: A Contrast Study of Oil Shale in Yaojie and Fushun Areas, China. [PDF]

ACS Omega
Wang L, Lu Y, Chen G, Xue L, Zhang Z, Wang S, Gao J.   +6 more
europepmc   +1 more source

Controlling - Grundzüge eines anspruchsgruppenspezifischen Konzepts mit verhaltenswissenschaftlicher Fundierung

Das Controlling hat seinen Platz in der Betriebswirtschaftslehre und damit als akademische Disziplin noch nicht gefunden, ja es ist nicht einmal allgemein geklärt, ob Controlling überhaupt eine wissenschaftliche Disziplin ist.
Lingnau, Volker
core  

Controlling információs rendszer bevezetése a Duna House-nál

, 2015
Témám a duna house-nál bevezetésre kerülő controlling rendszer bemutatása, bevezetésének az előzményei.
Dzsudzsák, Zsolt Szabolcs
core  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Distribution and Main Controlling Factors of Gas and Water in Tight Sandstone Gas Fields: A Case Study of Sudong 41-33 Block in Sulige Gas Field, Ordos Basin, China. [PDF]

ACS Omega
Xu T, Jia A, Huang Y, Fei S, Guo Z, Meng D, Feng N, Liu R, Wang C, Huang S.   +9 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Preliminary Analysis on the Main Control Factors of Shale Gas Accumulation [PDF]

Acta Geologica Sinica - English Edition, 2015
openaire   +1 more source