Results 81 to 90 of about 1,057,264 (313)

The impact of male contraception on dominance hierarchy and herd association patterns of African elephants (Loxodonta africana) in a fenced game reserve

Global Ecology and Conservation, 2014
Overpopulation of African elephants (Loxodonta africana) in fenced reserves in South Africa is becoming increasingly problematic to wildlife managers.
L.S. Doughty, K. Slater, H. Zitzer, Tomos Avent, S. Thompson   +4 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Space syntax analysis of the main square of Cusco

, 2018
El objetivo de estudio es la Plaza Mayor del Cusco. El presente artículo investiga el rol de la configuración urbana en el comportamiento del individuo en el espacio, por medio de la aplicación del enfoque sintáctico que caracteriza el estudio de las relaciones espaciales. Con este propósito, el método de estudio empleado, desarrollado por Bill Hillier
Legoas Calcine, Sheila Pamela, Torres Paredes, Edgar Alberto   +1 more
openaire   +1 more source

Detection of main tidal frequencies using least squares harmonic estimation method

Journal of Geodetic Science, 2012
AbstractIn this paper the efficiency of the method of Least Squares Harmonic Estimation (LS-HE) for detecting the main tidal frequencies is investigated. Using this method, the tidal spectrum of the sea level data is evaluated at two tidal stations: Bandar Abbas in south of Iran and Workington on the eastern coast of the UK. The amplitudes of the tidal
Mousavian R., Hossainali M. Mashhadi
openaire   +2 more sources

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Side C1 Street Square in the Light of Archaeological and Epigraphic Findings

Gephyra
The route of C Street, the main transport artery of the ancient city of Side, between the Main Gate and the Theatre buildings, is called C1. The square, located at the point where C1 Street provides access to the Main Gate and largely covered by modern ...
Volkan Öztekin
doaj   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

La esperanza del cuadrado medio Expectation of Square Means

Revista Colombiana de Ciencias Pecuarias, 2007
La esperanza del cuadrado medio es fundamental en el análisis de la varianza, para establecer la prueba F adecuada en el contraste de factores dispuestos en el diagrama de estructura bajo un modelo de clasificación experimental elegido por el ...
Luis F Restrepo B
doaj  

Effectiveness of a universal film intervention in reducing violence against children and increasing positive parenting among migrant and displaced caregivers from Myanmar: a community-based cluster randomised trialResearch in context

The Lancet Regional Health - Southeast Asia
Summary: Background: Parenting interventions have been shown to reduce violence against children and promote positive parenting, but evidence on interventions to achieve population-level reach and impact is limited in low-resource settings.
Amanda Sim, Khaing Zar Lwin, Stephanie Eagling-Peche, G.J. Melendez-Torres, Seema Vyas, Francisco Calderon, Tawanchai Jirapramukpitak, Jamie Lachman, Sureeporn Punpuing, Andrea Gonzalez, Mary Soan, Nway Nway Oo, Ivet Castello Mitjans, Greg Tyrosvoutis, Eve Puffer   +14 more
doaj   +1 more source