Results 61 to 70 of about 1,019,532 (266)

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Urban and architectural workshop Križevci, Ljutomer [PDF]

AR: Arhitektura, Raziskave, 2012
In the academic year 2011/2012 the students of the Faculty of Architecture with their mentor Tomaž Krušec conducted an Architectural and Urbanism Workshop at Križevci pri Ljutomeru 2011/2012.The workshop was organised by the Municipality of Križevci pri ...
Tomaž Krušec
doaj  

Using Field Trip as a Teaching Method: A Walking Tour of Timişoara as Seen by British Writers

Romanian Journal of English Studies, 2013
This article proposes a literary walking tour of Timişoara as seen by British authors who visited the city from the beginning of the 17th century to present.
Crişan Marius-Mircea
doaj   +1 more source

The Laguna’s main square: from holy ground to mundane stage

, 2021
Laguna constitui a terceira cidade mais antiga de Santa Catarina, considerada oficialmente fundada em 1676 com a posse das terras pelo colonizador Domingos Peixoto. Este manda erguer a Cruz do Cristianismo e, em 1696, uma singela Capela e seu adro, a área sagrada não construída à frente do edificado sacro, consagrando o lugar e explicitando a vitória ...
Benício, Danielle Rocha, Reitz, Lucas de Mello, Biava, Marciano Victor Biava Victor   +2 more
openaire   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Square-root relations between main saccadic parameters.

Investigative ophthalmology & visual science, 1997
To derive and evaluate two equations in which saccade duration and peak velocity are proportional to the square root of saccade amplitude.A population of horizontal visually guided saccades in a range of amplitudes from 1.5 degrees to 30 degrees was recorded by means of electro-oculography in eight normal adult subjects.
S, Lebedev, P, Van Gelder, W H, Tsui
openaire   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

The impact of male contraception on dominance hierarchy and herd association patterns of African elephants (Loxodonta africana) in a fenced game reserve

Global Ecology and Conservation, 2014
Overpopulation of African elephants (Loxodonta africana) in fenced reserves in South Africa is becoming increasingly problematic to wildlife managers.
L.S. Doughty, K. Slater, H. Zitzer, Tomos Avent, S. Thompson   +4 more
doaj   +1 more source

Detection of main tidal frequencies using least squares harmonic estimation method

Journal of Geodetic Science, 2012
AbstractIn this paper the efficiency of the method of Least Squares Harmonic Estimation (LS-HE) for detecting the main tidal frequencies is investigated. Using this method, the tidal spectrum of the sea level data is evaluated at two tidal stations: Bandar Abbas in south of Iran and Workington on the eastern coast of the UK. The amplitudes of the tidal
Mousavian R., Hossainali M. Mashhadi
openaire   +2 more sources