Results 131 to 140 of about 415,745 (375)

Universal Antibody‐Engineered Lipid Nanoparticles Potentiate Chemo‐Immunotherapy Against Triple‐Negative Breast Cancer by Reprogramming Tumor Cell Metabolism

open access: yesAdvanced Science, EarlyView.
A universal ROR1 antibody‐engineered lipid nanoparticle (LNP) is constructed by sequential drug encapsulation and antibody conjugation. The LNP not only enables enhanced chemotherapeutic efficiency by targeting drug delivery and precise localization of deep‐seated tumors through NIR‐II fluorescence imaging, but also remodels immunosuppressive TME ...
Yeneng Dai   +12 more
wiley   +1 more source

Generating Dynamic Structures Through Physics‐Based Sampling of Predicted Inter‐Residue Geometries

open access: yesAdvanced Science, EarlyView.
While static structure prediction has been revolutionized, modeling protein dynamics remains elusive. trRosettaX2‐Dynamics is presented to address this challenge. This framework leverages a Transformer‐based network to predict inter‐residue geometric constraints, guiding conformation generation via physics‐based iterative sampling. The resulting method
Chenxiao Xiang   +3 more
wiley   +1 more source

Single‐Cell Profiling: Any Scale, Any Size, All at Once

open access: yesAdvanced Science, EarlyView.
Traditional single‐cell technologies are constrained by cellular dimension and throughput scale, in addition to its inability preserve spatial information. With recent innovations, these technologies now allow high throughput, large‐sized cell, and multi‐modal profiling of patient samples, overcoming these limitations.
Denise Goh   +4 more
wiley   +1 more source

Heterointerface‐Functionalized Photoelectric Response of Metal‐Oxide Schottky Photodiode for Intelligent Fire Detection

open access: yesAdvanced Science, EarlyView.
A heterointerface‐functionalized Schottky photodiode (HF‐SPD) is developed to explore the photoelectric capabilities of low‐temperature oxide semiconductors. Besides the remarkable UV detection capability, the bias‐tunable photo response endows HF‐SPD with the unique wavelength selectivity.
Yuyang Cai   +13 more
wiley   +1 more source

Can organizational frameworks drive institutional change and results for gender equality? A case study of UNICEF

open access: yesGlobal Social Challenges Journal
The international development architecture, including multilateral institutions such as the United Nations, continues to play a significant role in the movement for gender equality.
Satvika Chalasani
doaj   +1 more source

INCLUSION OF CHILDREN WITH SPECIAL EDUCATIONAL NEEDS IN REGULAR SCHOOLS: STUDENTS ATTITUDES AND PERCEPTIONS [PDF]

open access: yesEconomy and Sociology, 2015
The Republic of Moldova started the process of deinstitutionalization of children with disabilities/and special educational needs and their inclusion in biological families and mainstream community based services.
Ludmila MALCOCI
doaj  

Resource capability for local government in mainstreaming gender into sustainable post disaster reconstruction : Evidence from Bantul Indonesia [PDF]

open access: yes
Understanding how local government responds to gender vulnerability and gender capacity is important to make cities safer both for women and for men.
Amaratunga, Dilanthi, Yumarni, Tri
core  

In from the margins: development and internationalisation within Irish universities [PDF]

open access: yes, 2009
Universities in Ireland, as elsewhere, are under severe pressure – indeed in crisis according to some commentators. The nature of this crisis is two-fold.
Gaynor, Niamh
core  

Nanozymes for Energy and Environmental Sustainability

open access: yesAdvanced Science, EarlyView.
At present, the widely used nanozymes are oxidoreductase and hydrolase, which have proved to have great application prospects in energy and environment. ABSTRACT Nanozymes have shown remarkable promise in addressing pressing challenges in energy and environmental sustainability.
Xiaoqi Li, Jinxing Chen, Shaojun Dong
wiley   +1 more source

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