STUDIES IN THE REFLEXES OF THE GUINEA‐PIG. VI.: ON THE RELATION BETWEEN MAINTAINED CONTRACTION AND RHYTHMIC DISCONTINUOUS INHIBITION [PDF]
T. Graham Brown
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Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona+4 more
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Method for Restoring and Maintaining Phenol Resistance of Certain Strains of Staphylococcus aureus [PDF]
Thomas C. Grubb, Marguerite A. Edwards
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Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura+8 more
wiley +1 more source
Conversion and fusion method of multi-source and different populations maintainability prior data. [PDF]
Zhou C, Xu D, Wang Z.
europepmc +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri+5 more
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National Assistance and The Liability To Maintain One's Family [PDF]
L. Neville Brown
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Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
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THE RELATION BETWEEN PLASMA PROTEIN CONTENT, PLASMA SPECIFIC GRAVITY AND EDEMA IN DOGS MAINTAINED ON A PROTEIN INADEQUATE DIET AND IN DOGS RENDERED EDEMATOUS BY PLASMAPHERESIS [PDF]
A. A. Weech+2 more
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Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source