Results 101 to 110 of about 13,846 (260)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Maintainability Assessment during the Design Phase: Integrating MTA and UNE 151001
MachinesThe focus on maintenance actions in the early design phases has been a trend in recent years. The main sources of information during the design of the maintainability process include operator reports, maintainer experience, failure history, and ...
Franco Donaire +3 more
doaj +1 more source
RAM-based Data Analytics for Power Plant Case Study: Steam Power Plant in Thailand [PDF]
E3S Web of ConferencesThis research project aims to improve a power plant maintenance program by using the theory of RAM (Reliability Availability and Maintainability). A North Bangkok Combined Cycle Power Plant, especially a steam turbines power plant, is selected to conduct
Talabgaew Sompoap, Suebsumran Anan
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
The impact of maintainability on component-based software systems
, 2003 There is a great deal of inconsistency and vagueness in the treatment of and terminology involved with software maintainability. This is exacerbated by the fact that there are a number of different dimensions of maintainability, each requiring specific ...
Matinlassi, Mari, Niemelä, Eila
core +1 more source
Sistemasi: Jurnal Sistem InformasiState management in modern mobile applications is a critical aspect that affects both user interface (UI) rendering performance and code maintainability. Previous studies on Flutter state management have generally used simple catalog applications as test
Muhammad Asep Subandri +2 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Development of a combat aircraft operational and cost-effectiveness design methodology [PDF]
, 2005 This study set out to develop an aircraft design methodology, which gives com- bat aircraft more operational and cost-effectiveness by considering these factors early in the design process.
Nilubol, Otsin
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source