Results 141 to 150 of about 166,212 (332)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

A Comparative Study of Rabbits Maintained on Barley or Alfalfa [PDF]

open access: bronze, 1932
Fritz Bischoff   +3 more
openalex   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

Preliminary Candidate Advanced Avionics System (PCAAS) [PDF]

open access: yes
Specifications which define the system functional requirements, the subsystem and interface needs, and other requirements such as maintainability, modularity, and reliability are summarized.
Hon, R. H., Smyth, R. K., Teper, G. L.
core   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Maintainability Allocation of EMUs Electric Traction Systems

open access: yes机车电传动, 2014
System maintainability allocation method was expounded. Function diagram and mathematical model on maintainability for EMUs electric traction systems were established, and weighted method was used for the distribution.
SHAO Zhi-he, HE-zai, LIU Xue-quan
doaj  

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