Results 111 to 120 of about 5,334,868 (308)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Advanced periodic maintenance scheduling methods for aircraft lifecycle management [PDF]
, 2013 This paper reviews existing methods and techniques addressing the problem of maintenance support throughout the life cycle for high value manufacturing products such as aircrafts.
Fedotova, Alena +2 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Effect of Two Weight Reduction Maintenance Strategies for Moderately/Mildly Retarded Adults [PDF]
, 1986 Thirteen retarded adult subjects were first exposed to a 12-week behavior therapy weight reduction program followed by a ten-month weekly weigh-in. Then the subjects were randomly assigned to an experimental maintenance booster session group (n=7) or a ...
Fox, Robert +5 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Knowledge-based and Expert Systems in Prognostics and Health Management: a Survey
International Journal of Prognostics and Health ManagementPrognostics and Health Management (PHM) has become increasingly popular in recent years, and data-driven methods and artificial intelligence have emerged as dominant tools within the PHM field.
Kalil Bouhadra, Florent Forest
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Modeling Maintenance Productivity Measurement of Engineering Production Systems: Discrete Event Simulation Approach [PDF]
, 2013 Modeling and simulation of industrial information communication systems and networks is one of the major concerns of productivity engineers for the establishment of productivity standards in virtually all functional areas of an industrial organization.
Bolu, Christian
core +1 more source
Frontiers in Drug Safety and RegulationThe COVID-19 pandemic has had a profound impact on global public health, infecting over 770 million individuals and resulting in more than 6.9 million deaths worldwide.
Brian O’Hare +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source