Results 91 to 100 of about 5,334,868 (308)
ElectricaTo address issues such as inadequate fault tolerance, long computation time, and limited universality in fault location for active distribution networks, this paper proposes a fault location method that combines Petri nets with an improved particle swarm
Yunfeng Xia +4 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The adoption and use of Through-life Engineering Services within UK Manufacturing Organisations [PDF]
, 2014 Manufacturing organisations seek ever more innovative approaches in order to maintain and improve their competitive position within the global market. One such initiative that is gaining significance is ‘through-life engineering services’.
Phillips, Paul +4 more
core +1 more source
Reliability Analysis of Switches and Crossings – A Case Study in Swedish Railway [PDF]
International Journal of Railway Research, 2017 It is reported that switches and crossings (S&C) are one of the subsystems that cause the most delays on Swedish Railways while accounting for at least 13% of maintenance costs.
Behzad Ghodrati +2 more
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Journal of Engineering and Applied ScienceThe precise forecasting of the Remaining Useful Life (RUL, expressed in hours) of aircraft engine-like systems using a synthetic dataset designed to mimic real engine degradation patterns is a key factor in setting up maintenance schedules that are cost ...
Yankai Bi, Chao Wang, Yuan Chi
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Diagnostics and prognostics utilising dynamic Bayesian networks applied to a wind turbine gearbox [PDF]
, 2012 The UK has the largest installed capacity of offshore wind and this is set to increase significantly in future years. The difficulty in conducting maintenance offshore leads to increased operation and maintenance costs compared to onshore but with better
Kenyon, Andrew +4 more
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source