Results 91 to 100 of about 71,800 (241)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Nanotherapeutics for Macrophage Network Modulation in Tumor Microenvironments: Targets and Tools

International Journal of Nanomedicine
Renwei Li,1,* Jing Huang,2,* Yuhao Wei,1 Yusha Wang,1,3 Can Lu,4,5 Jifeng Liu,6,7 Xuelei Ma1 1Department of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041 ...
Li R, Huang J, Wei Y, Wang Y, Lu C, Liu J, Ma X   +6 more
doaj  

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Flexible wearable sensors for sports training: recent advances and future perspectives

Materials & Design
Modern sports training increasingly demands objective, continuous, and real-time monitoring of athletes’ multidimensional physiological states. Conventional technologies are constrained by invasiveness, susceptibility to motion artifacts, and limited ...
Hongfu Jin, Wenwu Wang, Sijie Chen, Guoxu Zhang, Yao Tong, Dan Lu, Jian Li, Liang He, Xin Tang   +8 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Advances in flexible wearable pressure/strain sensors for motion monitoring in orthopaedic sports medicine

Journal of Orthopaedic Translation
The growing demand for real-time, high-resolution motion monitoring in orthopaedic sports medicine is driving the development of flexible wearable pressure/strain sensors.
Hongfu Jin, Wenwu Wang, Guoxu Zhang, Sijie Chen, Yao Tong, Dan Lu, Jian Li, Liang He, Xin Tang   +8 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Identifying and Analyzing Investment Risks in Hospital Wastewater Infrastructure Using the FMEA Method [PDF]

بیمارستان
Background and purpose: Hospital wastewater infrastructure is critical for safeguarding public health and protecting the environment. Deficiencies in the management of these systems can precipitate severe public health and environmental crises.
Abbas Jahangiri
doaj  

Gantry-period-guided modulation factor selection in helical tomotherapy: effects on delivery efficiency, dosimetry and verification accuracy

Frontiers in Oncology
PurposeTo explore a gantry-period-guided strategy for identifying a lower useful modulation factor (MF) in helical tomotherapy under fixed field width and pitch.MethodsTwenty previously treated cases from head, head-and-neck, abdomen and pelvis were ...
Xiaoli Jin, Tianhui Gao, Xiangqian Liu, Hailiang Zhang, Xin Yang, Xia Zhang   +5 more
doaj   +1 more source