Results 61 to 70 of about 1,371,472 (303)

The Importance of Preventive and Corrective Maintenance in Works [PDF]

open access: yes, 2018
The present study addresses the problems brought by the lack of preventive and corrective maintenance. The purpose of this work is to focus on the importance of preventive and corrective maintenance, for the prevention and conservation of engineering ...
Balduino, Â. R. (Ângelo)   +1 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

AN EXAMINATION OF THE RELATIONSHIP BETWEEN SUPPLY CHAIN MANAGEMENT PRACTICES AND BUSINESS PERFORMANCE: A CASE ANALYSIS OF A PASSENGER RAIL COMPANY

open access: yesSouth African Journal of Industrial Engineering, 2018
The lack of maintenance engineering performance is one of the main causes of poor service delivery. In a passenger rail company, maintenance engineering performance is measured using several parameters, which include the ability of the organisation to ...
Fourie, Cornelius Jacobus   +1 more
doaj   +1 more source

Aplikasi Pelayanan Pengaduan Maintenance Divisi Teknik Berbasis Android Pada Perguruan Tinggi Raharja [PDF]

open access: yes, 2019
Development of Service System for engineering section in the form of Application Maintenance Request System, which is used to improve services only to management, namely staf.
Aris, A. (Aris)   +2 more
core  

Benchmarking of project planning and success in selected industries [PDF]

open access: yes, 2015
Purpose - To identify the industry in which projects are best planned and executed and use it as a benchmark for improving project planning in other industries.
Globerson, Shlomo, Zwikael, Ofer
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Fault analysis of industrial robots based on self-organised critical theory

open access: yesThe Journal of Engineering, 2019
Industrial robots, as a structurally sophisticated mechatronics system, have a high cost of routine maintenance and repair. Repairs after fault require the corresponding manpower and material resources, and have hysteresis.
Yuming Qi   +3 more
doaj   +1 more source

Towards an integrated perspective on fleet asset management: engineering and governance considerations [PDF]

open access: yes, 2008
The traditional engineering perspective on asset management concentrates on the operational performance the assets. This perspective aims at managing assets through their life-cycle, from technical specification, to acquisition, operation including ...
Kivits, Rob   +3 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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