Results 51 to 60 of about 660,261 (307)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Maintenance Knowledge Management with Fusion of CMMS and CM [PDF]

open access: yes, 2013
- Maintenance can be considered as an information, knowledge processing and management system. The management of knowledge resources in maintenance is a relatively new issue compared to Computerized Maintenance Management Systems (CMMS) and Condition ...
Singh, Sarbjeet   +4 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

METHODS AND TECHNIQUES OF PREDICTION OF KEY PERFORMANCE INDICATORS FOR IMPLEMENTATION OF CHANGES IN MAINTENANCE ORGANISATION [PDF]

open access: yesManagement Systems in Production Engineering, 2012
The article presents the concept of how to assess the future state of the organization in the area of using and maintenance of technical means, basing on the combination of "classic" prognostic model with models ‐ components of the selected computer ...
Andrzej WIECZOREK
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Management of Maintenance on an e-Maintenance Platform

open access: yes, 2017
Maintenance of assets is an important part of the asset life cycle. Emergence ofe-technologies has enabled faster and efficient maintenance activities withe-maintenance. This paper presents a maintenance management model on ane-maintenance platform, which uses Return on Investment (RoI) as the criteria for decision-making.
Jantunen, Erkki   +4 more
openaire   +4 more sources

The Impact of Integrating Information Technology With Operational Technology in Physical Assets: A Literature Review

open access: yesIEEE Access
The convergence of information technology (IT) with operational technology (OT), within physical assets can enhance performance but also presents challenges due to higher performance expectations and increased complexity.
Arno Kok   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Quantitative Analysis of Criteria in University Building Maintenance in Malaysia

open access: yesAustralasian Journal of Construction Economics and Building, 2010
University buildings are a significant part of university assets and considerable resources are committed to their design, construction and maintenance.
Olanrewaju Ashola Abdul-Lateef
doaj   +1 more source

Barriers in managing the maintenance activity: towards sustainable and lean maintenance approach [PDF]

open access: yes, 2018
Venue: TH Hotel, Alor Setar, Kedah, Malaysia.This paper present on the preliminary findings of pilot project aimed at exploring the issue related to managing the maintenance activity in Malaysian Small and Medium Enterprises (SMEs).
Adnan Bakri   +2 more
core  

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