Results 171 to 180 of about 2,626,327 (351)
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
AN INFLATION-BASED MAINTENANCE SCHEDULING MODEL
<p>ENGLISH ABSTRACT: This paper attempts to extend an original Gantt-charting model for optimal maintenance scheduling of multiple facilities in multiple periods credited to Charles- Owaba. In particular, an inflationary factor is incorporated into
S.A. Oke, O.E. Charles-Owaba
doaj
Improving workforce scheduling of aircraft line maintenance at Sabena Technics. [PDF]
This paper presents our application of a visualization tool and optimization model based on mixed-integer linear programming to solve a workforce staffing and scheduling problem at Sabena Technics, a major aircraft maintenance company in Belgium. We used
Belien, Jeroen +2 more
core
Insights into a long life without cancer: The case of the bowhead whale
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
FAKTOR PENYEBAB KERUSAKAN SISTEM MESIN PADA BUS APTB PPD
Comfort and safety of public transportation, particularly APTB PPD buses, becomes high expectations for its customers. Those expectations must be supported by the application of a good engine maintenance system.
Laela Chairani +2 more
doaj
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source

