Results 151 to 160 of about 2,626,327 (351)
EnergiesMaintenance scheduling of hydropower units is essential for ensuring the operational security and stability of large-scale cascaded hydropower systems and for improving the efficiency of water energy utilization.
Le Li +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Constraint-based scheduling [PDF]
The GERRY scheduling system developed by NASA Ames with assistance from the Lockheed Space Operations Company, and the Lockheed Artificial Intelligence Center, uses a method called constraint-based iterative repair. Using this technique, one encodes both
Zweben, Monte
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
A column generation approach to solve the crew re-scheduling problem [PDF]
When tracks are out of service for maintenance during a certainperiod, trains cannot be operated on those tracks. This leads to amodified timetable, and results in infeasible rolling stock andcrew schedules. Therefore, these schedules need to be repaired.
Huisman, D.
core +1 more source
Analisa Penjadwalan Dan Biaya Perawatan Mesin Press Untuk Pembentukan Kampas Rem [PDF]
, 2000 Maintenance scheduling system is very important for a company to reduce total maintenance cost. Maintenace scheduling will be done on hydraulic seal and oil burner pipe that are components of press machine for hot forming process.
Wahjudi, D. (Didik), Amelia, A. (Amelia)
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Genetic and memetic algorithms for scheduling railway maintenance activities [PDF]
Nowadays railway companies are confronted with high infrastructure maintenance costs. Therefore good strategies are needed to carry out these maintenance activities in a most cost effective way.
Budai-Balke, G., Dekker, R., Kaymak, U.
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source