Results 151 to 160 of about 652,724 (310)

Exploring the effect of chidamide on blastic plasmacytoid dendritic cell neoplasm: a case report and literature review

open access: yesTherapeutics and Clinical Risk Management, 2018
Shunan Wang,1 Wei Guo,1 Xin Wan,1 Yongliang Teng,2 Xiaoge Zhou,3 Ou Bai1 1Department of Hematology, 2Department of Pathology, The First Hospital of Jilin University, Changchun, 3Department of Pathology, Beijing Friendship Hospital, Capital Medical ...
Wang S   +5 more
doaj  

Thinking about thinking: an exploration of metacognitive factors in the development and maintenance of positive psychotic symptoms

open access: yes, 2013
The literature review discusses the role of metacognition, defined as the cognitive processes involved in ‘thinking about thinking’, in the development and maintenance of persecutory delusions and auditory hallucinations. Much of the literature points to
Norman, Catherine
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Efficacy and Safety of Maintenance Therapy Using Cetuximab in Patients with Metastatic Colorectal Cancer: Retrospective Study

open access: yesCancer Management and Research
Tiantian Xuan,1 Zhanmei Wang,1 Sibo Meng,1 Jiaxin Li,1 Jisheng Li,2 Fangli Cao,1,* Linli Qu1,* 1Department of Medical Oncology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, Shandong, People’s Republic of ...
Xuan T   +6 more
doaj  

Is maintenance fluid therapy in need of maintenance?

open access: yesCritical Care and Resuscitation, 2013
David J, Gattas, Manoj K, Saxena
openaire   +2 more sources

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Maintenance ECT in a patient with catatonic schizophrenia and tardive dyskinesia

open access: yes, 1996
We describe a 44-year-old-man with a 14-year history of catatonic schizophrenia and a 2-year history of tardive dyskinesia. Because of the worsening course of his illness in recent months, characterized by resistance to antipsychotic drugs and 4 ...
Ucok, G, Ucok, A
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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