Results 21 to 30 of about 1,549,556 (233)
Structural basis of the amidase ClbL central to the biosynthesis of the genotoxin colibactin
Insight into biosynthetic pathways in the human microbiome can provide details of host–microbe interactions and beneficial symbiosis. In this report, the structure and function of a key bond‐forming enzyme in the biosynthesis of the human genotoxin colibactin is presented.Colibactin is a genotoxic natural product produced by select commensal bacteria ...
Prabhanshu Tripathi +3 more
wiley +1 more source
Abstract Despite widespread and worldwide efforts to eradicate vector‐borne diseases such as malaria, these diseases continue to have an enormous negative impact on public health. For this reason, scientists are working on novel control strategies, such as gene drive technologies (GDTs).
Nienke de Graeff +4 more
wiley +1 more source
Abstract Objective Optimising antibiotic use is important to limit increasing antibiotic resistance. In rural Burkina Faso, over‐the‐counter dispensing of antibiotics in community pharmacies and non‐licensed medicine retail outlets facilitates self‐medication. We investigated its extent, reasons and dispensing patterns.
Daniel Valia +14 more
wiley +1 more source
Nanofluids are generally utilized in providing cooling, lubrication phenomenon, and controlling the thermophysical properties of the working fluid. In this paper, nanoparticles of Al2O3 are added to the base fluid, which flows through the counterflow arrangement in a turbulent flow condition.
Debabrata Barik +5 more
wiley +1 more source
Objective We examined the cost‐effectiveness of treatment strategies for concomitant meniscal tear and knee osteoarthritis (OA) involving arthroscopic partial meniscectomy surgery and physical therapy (PT). Methods We used the Osteoarthritis Policy Model, a validated Monte Carlo microsimulation, to compare three strategies, 1) PT‐only, 2) immediate ...
Emma E. Williams +10 more
wiley +1 more source
Abstract Aeolianites with a mixed clastic and carbonate detrital mineralogy are typical deposits of tropical coastal desert environments. These deposits are genetically related to transgressive–regressive cycles, with the shallow‐marine carbonate detrital component being deflated from the exposed seafloor during episodes of glacial sea‐level lowstands,
Francesco Arboit +5 more
wiley +1 more source
Scientific realism and underdetermination in quantum theory
Abstract This paper surveys the status of scientific realism in relation to quantum physics, focusing on the problem of underdetermination.
Matthias Egg, Juha Saatsi
wiley +1 more source
Abstract There is a long tradition of preferring local theories to ones that posit lawful or causal influence at a spacetime distance. In this paper, we argue against this preference. We argue that nonlocality is scientifically unobjectionable and that nonlocal theories can be known.
Heather Demarest, Michael Townsen Hicks
wiley +1 more source
Este artigo discute de forma concisa conceitos chaves do modo de produção capitalista, apartir de O Capital de Karl Marx. Parte-se da premissa que há em O Capital uma unidadelógica, senão dialética, para compreender suas categorias, conceitos e suas ...
Adrián Sotelo Valencia
doaj +1 more source

