Results 161 to 170 of about 49,830 (288)

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

Advanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang, Xinyan Sun, Yingchao Sun, Zeqiang Cheng, Zixiang Cheng, Shengbo Han, Ying Feng, Wenbo Yang, Huimin Li, Meichen Zhu, Xiaoling Wu, Jinghua Zhang, Jihua Tang, Honglian Li, Yanyong Cao, Canxing Duan, Yan Shi   +16 more
wiley   +1 more source

Impact of Spontaneous Haploid Genome Doubling in Maize Breeding. [PDF]

Plants (Basel), 2020
Boerman NA, Frei UK, Lübberstedt T.
europepmc   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

A new isolation device for shortening gene flow distance in small-scale transgenic maize breeding. [PDF]

Sci Rep, 2020
Zhang L, Huo S, Cao Y, Xie X, Tan Y, Zhang Y, Zhao H, He P, Guo J, Xia Q, Zhou X, Long H, Guo A.   +12 more
europepmc   +1 more source

Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis

Advanced Science, EarlyView.
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim, Ha Kyeong Lee, Zulfikar Azam, Jeong Uk Choi, Riajul Wahab, Na Kyeong Lee, Yoon Gun Ko, So‐Young Choi, Se‐Ra Lee, Wan Seob Shim, Taeeung Kim, In‐San Kim, Farzana Alam, Sang Yoon Kim, Seong Who Kim, Youngro Byun, Taslim A Al‐Hilal   +16 more
wiley   +1 more source

QTL KARTIRANJE ZA SVOJSTVA KVALITETE ZRNA KOD TESTKRIŽANACA BIPARENTALNE POPULACIJE KUKURUZA KORIŠTENJEM PODATAKA GENOTIPIZACIJE SEKVENCIRANJEM

Poljoprivreda, 2017
Proveli smo QTL kartiranje u test križancima IBMSyn4 populacije za tri svojstva kvalitete zrna: sadržaj ulja i proteina te hektolitarsku masu. 191 fenotipizirana i genotipizirana linija korištena je kao “training” populacija, dok je 85 linija, koje su ...
Mario Franić, Antun Jambrović, Zvonimir Zdunić, Andrija Brkić, Domagoj Šimić, Vlatko Galić   +5 more
doaj  

Multiple-trait, random regression, and compound symmetry models for analyzing multi-environment trials in maize breeding. [PDF]

PLoS One, 2020
Ferreira Coelho I, Peixoto MA, Santana Pinto Coelho Evangelista J, Silva Alves R, Sales S, Resende MDV, Naves Pinto JF, Fialho Dos Reis E, Bhering LL.   +8 more
europepmc   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T. Rosen, Yingyu Wang, Chun‐Wei D. Chen, Cheng Zhang, Mingye Feng   +12 more
wiley   +1 more source

Adoption of Conservation Agriculture Technologies by Smallholder Farmers in the Shamva District of Zimbabwe: A Tobit application [PDF]

Conventional agricultural practices such as the use of the moldboard plough are no longer sustainable due to their extensive soil degradation effects.
Chiputwa, Brian, Langyintuo, Augustine S., Wall, Patrick   +2 more
core   +1 more source