Results 31 to 40 of about 44,748 (260)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Seed Weight as a Covariate in Association and Prediction Studies for Biomass Traits in Maize Seedlings

Plants, 2020
Background: The seedling stage has received little attention in maize breeding to identify genotypes tolerant to water deficit. The aim of this study is to evaluate incorporation of seed weight (expressed as hundred kernel weight, HKW) as a covariate ...
Vlatko Galic, Maja Mazur, Andrija Brkic, Josip Brkic, Antun Jambrovic, Zvonimir Zdunic, Domagoj Simic   +6 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

The prospects for using haploinducers in maize breeding

Plant Biotechnology and Breeding, 2020
The discovery of spontaneous haploid plants and the development of ways to produce them inin vitroculture have set a new direction important for breeding and for theoretical research in reproductive biology. The frequency of spontaneous haploidy in cultivated plants is extremely low and does not exceed 0.01-0.1%, therefore, the search for sources and ...
G. M. Asadova, A. V. Ulyanov, M. V. Karlov, E. B. Khatefov   +3 more
openaire   +3 more sources

Maize breeding for sustainable agricultural systems

Revista Verde de Agroecologia e Desenvolvimento Sustentável, 2021
In the present work, a recurrent selection program was initiated, between and within half-sib families in landrace maize, with the objective of obtaining, at the end of the process, a productive maize variety for agroecological cultivation systems adapted to the northeast region.
Matheus Lima Oliveira, Lucas Nunes da Luz, Ana Kelly de Sousa Julião, Antonio Fabio da Silva Lima, Francisco Aglauberto de Lima Gouveia, Maryssol Torres Gadelha   +5 more
openaire   +3 more sources

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Discrepant involvement of homologous repair and non-homologous end joining pathways in maize development and growth

Crop Journal
Chromosomal DNA double-strand breaks (DSBs) are often generated in the genome of all living organisms. To combat DNA damage, organisms have evolved several DSB repair mechanisms, with nonhomologous end-joining (NHEJ) and homologous recombination (HR ...
Shuanghui Zhao, Leiming Zheng, Minghui Zheng, Menghan Li, Shuyue Li, Nan Wu, Yan He, Jinghan Liu   +7 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Molecular markers in maize breeding [PDF]

Selekcija i Semenarstvo, 2011
Today the marker assisted selection (MAS) is being routinely applied in breeding programs of large private companies. However, the implementation of molecular markers for commercial use in small companies and public sec- tor is on a considerably smaller scale.
Treskić, Sanja, Ivanović, Mile, Kobiljski, Borislav, Kondić-Špika, Ankica, Brbaklić, Ljiljana, Trkulja, Dragana, Stanisavljević, Dušan, Mitrović, Bojan   +7 more
openaire   +1 more source