Results 311 to 320 of about 1,028,298 (351)

An Innovative “Tooth‐On‐Chip” Microfluidic Device Emulating the Structure and Physiology of the Dental Pulp Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Alessandro Cordiale   +6 more
wiley   +1 more source

Natural variation in the ZmPIMT1 promoter enhances seed aging tolerance by regulating PABP2 repair in maize. [PDF]

open access: yesPlant Cell
Zhang Y   +15 more
europepmc   +1 more source

Coordinated Development of Immune Cell Populations in Vascularized Skin Organoids from Human Induced Pluripotent Stem Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Vascularized skin organoids are developed from human induced pluripotent stem cells and contain macrophages, Langerhans cells, and neutrophils. Vascularized skin organoids offer a transformative platform to model skin biology and enable mechanistic investigations of inflammatory and hematologic skin disorders.
Mitchell Mostina   +9 more
wiley   +1 more source

Photoactivated Proximity Protein Labeling Reveals Enhanced Tumor Retention of a D‐Peptide‐Ruthenium Prodrug Conjugate

open access: yesAdvanced Healthcare Materials, EarlyView.
Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang   +7 more
wiley   +1 more source

Fabrication of Patterned Composite Microneedles via Inkjet Printing for Enhanced Drug Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel inkjet printing‐based microneedle platform enabling multi‐material fabrication for customizable and scalable transdermal drug delivery. Abstract Microneedle (MN) technology offers a minimally invasive, patient‐friendly alternative to conventional hypodermic injections for dermal drug delivery.
Sanghyeok Jang   +2 more
wiley   +1 more source

Uniting 4D Printing and Melt Electrowriting for the Enhancement of Regenerative Small Diameter Vascular Grafts

open access: yesAdvanced Healthcare Materials, EarlyView.
A hybrid 4D printing strategy enables the fabrication of shape‐morphing, mechanically reinforced tubular constructs for vascular tissue engineering. By combining alginate‐methylcellulose hydrogels with melt electrowritten polycaprolactone fibers and protein‐based functionalization, this platform supports spatially organized co‐cultures of fibroblasts ...
Max von Witzleben   +8 more
wiley   +1 more source

When crops fail, forests follow: Agricultural shocks and deforestation in Zambia. [PDF]

open access: yesProc Natl Acad Sci U S A
Ordóñez PJ   +3 more
europepmc   +1 more source

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