Results 91 to 100 of about 227,905 (243)

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

Advanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin, Yu Zhang, Xinyu Qu, Jiayi Liu, Zhongyi Sun, Haibo Liu, Ziyan Chen, Jing Ru, Jingwen Han, Bingqiang Lu, Yan Lu, Yan Wang, Xinyu Zhao, Feng Chen   +13 more
wiley   +1 more source

Optimizing sowing dates increase solar radiation to mitigate maize lodging and yield variability: A five-year field study

Journal of Integrative Agriculture
Optimizing sowing dates (SDs) represents a viable strategy for adapting maize production to climate change and enhancing yield. However, research remains limited regarding the integrated effects of lodging and yield in relation to climatic variables ...
Xinglong Wang, Fan Liu, Nan Zhao, Xia Du, Pijiang Yin, Tongliang Li, Tianqiong Lan, Dongju Feng, Fanlei Kong, Jichao Yuan   +9 more
doaj   +1 more source

High-throughput micro-phenotyping measurements applied to assess stalk lodging in maize (Zea mays L.)

Biological Research, 2018
Background The biomechanical properties of maize stalks largely determine their lodging resistance, which affects crop yield per unit area. However, the quantitative and qualitative relationship between micro-phenotypes and the biomechanics of maize ...
Ying Zhang, Jianjun Du, Jinglu Wang, Liming Ma, Xianju Lu, Xiaodi Pan, Xinyu Guo, Chunjiang Zhao   +7 more
doaj   +1 more source

CGIAR Research Program on Maize - Plan of Work and Budget 2021

, 2021
Led by the International Maize and Wheat Improvement Center (CIMMYT), with the International Institute of Tropical Agriculture (IITA) as its main CGIAR Consortium partner, The CGIAR Agri-food Research Program MAIZE focuses on increasing maize production ...
CGIAR Research Program on Maize
core  

Targeting p21‐High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

Advanced Science, EarlyView.
Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta, Shuyi Wang, Boyan Zhang, Ning Liu, Yingchen Han, Aoran Liu, Ying Xu, Tingsong Chen, Ye Zhang, Qiuhua Luo, Tao Han   +10 more
wiley   +1 more source

PDGFRα+/Integrin α2+ Fibroblasts Orchestrate Tumor Budding in Oral Squamous Cell Carcinoma via Mechano‐Metabolic Symbiosis: E‐Cadherin/Integrin α2β1 Adhesion and Mitochondrial Transfer

Advanced Science, EarlyView.
PDGFA/PDGFRα signaling recruits CAFs to OSCC nests, and CAF‐OSCC contact drives tumor budding invasion. Mechanistically, heterotypic adhesion via E‐cadherin/integrin α2β1 activates YAP signaling in OSCC cells, inducing EMT. Concurrently, CAFs transfer mitochondria through TNTs, supplying ATP to fuel invasion.
Yufang Liu, Jiao Li, Juan Liu, Qi Dong, Haoyang Zhang, Yanjin Wang, Huibing Li, Ye Guan, Lei Cao, Manqing Zhang, Fangning Guo, Xue Liu, Zhen Yang, Mengmeng Lu, Hui Liu, Laiping Zhong, Tong Ji, Tingjiao Liu   +17 more
wiley   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng, Mengmeng Wang, Kang Wang, Zhuo Xing, Yulong Hong, Tongtong Li, Geng Zong, Chong Yang, Dan Zhang, Zhangling Chen, Xin Jin   +10 more
wiley   +1 more source

Annual progress report 2013: CGIAR Research Program on Maize

, 2014
Annual progress report 2013: CGIAR Research Program on Maize ...
CGIAR Research Program on Maize
core   +1 more source

Assessment on Risk of Gale Disaster in Different Growth Stages of Summer Maize in North China Plain

Shuitu baochi yanjiu
[Objective] Gale disaster is one of the main meteorological disasters that restrict social and economic development. The aim of this study is to scientifically assess the risk of gale disaster, which is of great significance for disaster prevention and ...
Wu Yaxin, He Qijin, Liu Jiahong, Xiao Xiao, Sun Weiwei, Shi Yuxin, Zhou Kexin, Zhou Sijia, Ma Selimai, Wang Rongwan   +9 more
doaj  

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization

Advanced Science, EarlyView.
In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin, Shicong Zheng, Pei Song, Jie Chang, Zewei Chen, Cang Li, Min Yu, Lude Wang, Shian Yu   +8 more
wiley   +1 more source