Results 161 to 170 of about 8,230,812 (271)

Therapeutic orphans no more: Revisiting the ethical justification for excluding pregnant women from pharmaceutical clinical trials

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract For six decades, pregnant women have been routinely excluded from pharmaceutical clinical trials, a practice rooted in a protectionist ethic that emerged after the thalidomide tragedy. This narrative review examines whether that exclusion remains ethically justifiable, drawing on the obstetric, pharmacological, and bioethical literature ...
Camila Kruger Cabar   +1 more
wiley   +1 more source

Translating Riedl: The Circulation and Operationalisation of Evolutionary Ideas

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Rupert Riedl's Order in Living Organisms proposed a systems theory of evolution decades before the concepts it pioneered—homology, burden, the imitative epigenotype—reached the agenda of evolutionary biology. This paper reconstructs the lineages that operationalized his insights across several fields and explores the internal and external reasons for ...
Laura Nuño de la Rosa
wiley   +1 more source

RECiPROsody: A Study Protocol for Investigating Movement and Prosodic Synchrony as Embodied Markers of Relational Attunement in Gestalt Psychotherapy

open access: yesThe Journal of Humanistic Counseling, EarlyView.
ABSTRACT Nonverbal synchrony supports therapeutic alliance, yet its role in Gestalt psychotherapy remains underexplored. This manuscript presents the RECiPROsody study protocol, designed to investigate how multimodal interpersonal synchrony between therapists and clients relates to embodied attunement and therapeutic outcomes.
Serena Iacono Isidoro   +7 more
wiley   +1 more source

A real‐world analysis of AI chatbot performance for medicines information enquiries

open access: yesJournal of Pharmacy Practice and Research, EarlyView.
Abstract Background The provision of medicines information (MI) services requires interpretation and clinical judgement of complex scenarios by pharmacists. To date, few studies have assessed the performance of artificial intelligence (AI) chatbots to assist pharmacists providing MI advice.
Duncan Yorkston   +2 more
wiley   +1 more source

Major Adverse Limb Events and Death After Successful Endovascular Revascularization: BEST-CLI Trial. [PDF]

open access: yesJ Soc Cardiovasc Angiogr Interv
Kinlay S   +13 more
europepmc   +1 more source

Pembrolizumab‐Induced Subacute Cutaneous Lupus Erythematosus: A Case Report

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Subacute cutaneous lupus erythematosus (SCLE) is an increasingly recognized cutaneous immune‐related adverse event of immune checkpoint inhibitors. We report an 83‐year‐old woman who developed pruritic annular and polycyclic plaques 10 weeks after starting pembrolizumab for oropharyngeal squamous cell carcinoma.
Sebastiano Posenato   +5 more
wiley   +1 more source

Development and External Validation of a Postoperative Risk Score for Venous Thromboembolism in Epithelial Ovarian Cancer

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a major complication in women with epithelial ovarian cancer (EOC). We aimed to develop and externally validate an early postoperative risk score to identify EOC patients at increased risk of VTE after debulking surgery.
Qiu‐Lin Cui   +6 more
wiley   +1 more source

Alcohol use disorder increases risk of major adverse limb events following lower-extremity revascularization for chronic limb-threatening ischemia. [PDF]

open access: yesJ Vasc Surg
Machinski SN   +8 more
europepmc   +1 more source

Association of Mammographic Features and Major Adverse Cardiac Events in Postmenopausal Women: A 10-Year Retrospective Cohort Study [PDF]

open access: yes
Yunting Hu, Zheng Wang, Zengfa Huang, Yun Hu, Xiang Wang Department of Radiology, the Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430013, People’s Republic of ChinaCorrespondence: Xiang ...
Hu Y, Huang Z, Wang X, Wang Z
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