Abstract For six decades, pregnant women have been routinely excluded from pharmaceutical clinical trials, a practice rooted in a protectionist ethic that emerged after the thalidomide tragedy. This narrative review examines whether that exclusion remains ethically justifiable, drawing on the obstetric, pharmacological, and bioethical literature ...
Camila Kruger Cabar +1 more
wiley +1 more source
Association Between Intra-Leg Ankle-Brachial Index Asymmetry and Major Adverse Limb Events in Patients with Peripheral Artery Disease. [PDF]
Li B +7 more
europepmc +1 more source
Translating Riedl: The Circulation and Operationalisation of Evolutionary Ideas
Rupert Riedl's Order in Living Organisms proposed a systems theory of evolution decades before the concepts it pioneered—homology, burden, the imitative epigenotype—reached the agenda of evolutionary biology. This paper reconstructs the lineages that operationalized his insights across several fields and explores the internal and external reasons for ...
Laura Nuño de la Rosa
wiley +1 more source
ABSTRACT Nonverbal synchrony supports therapeutic alliance, yet its role in Gestalt psychotherapy remains underexplored. This manuscript presents the RECiPROsody study protocol, designed to investigate how multimodal interpersonal synchrony between therapists and clients relates to embodied attunement and therapeutic outcomes.
Serena Iacono Isidoro +7 more
wiley +1 more source
A real‐world analysis of AI chatbot performance for medicines information enquiries
Abstract Background The provision of medicines information (MI) services requires interpretation and clinical judgement of complex scenarios by pharmacists. To date, few studies have assessed the performance of artificial intelligence (AI) chatbots to assist pharmacists providing MI advice.
Duncan Yorkston +2 more
wiley +1 more source
Major Adverse Limb Events and Death After Successful Endovascular Revascularization: BEST-CLI Trial. [PDF]
Kinlay S +13 more
europepmc +1 more source
Pembrolizumab‐Induced Subacute Cutaneous Lupus Erythematosus: A Case Report
ABSTRACT Subacute cutaneous lupus erythematosus (SCLE) is an increasingly recognized cutaneous immune‐related adverse event of immune checkpoint inhibitors. We report an 83‐year‐old woman who developed pruritic annular and polycyclic plaques 10 weeks after starting pembrolizumab for oropharyngeal squamous cell carcinoma.
Sebastiano Posenato +5 more
wiley +1 more source
ABSTRACT Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a major complication in women with epithelial ovarian cancer (EOC). We aimed to develop and externally validate an early postoperative risk score to identify EOC patients at increased risk of VTE after debulking surgery.
Qiu‐Lin Cui +6 more
wiley +1 more source
Alcohol use disorder increases risk of major adverse limb events following lower-extremity revascularization for chronic limb-threatening ischemia. [PDF]
Machinski SN +8 more
europepmc +1 more source
Association of Mammographic Features and Major Adverse Cardiac Events in Postmenopausal Women: A 10-Year Retrospective Cohort Study [PDF]
Yunting Hu, Zheng Wang, Zengfa Huang, Yun Hu, Xiang Wang Department of Radiology, the Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430013, People’s Republic of ChinaCorrespondence: Xiang ...
Hu Y, Huang Z, Wang X, Wang Z
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