Prediction of 1-Year Major Adverse Cardiovascular Events in Chronic Limb Threatening Ischemia
Background: Patients with chronic limb threatening ischemia (CLTI) are at risk for major adverse cardiovascular events (MACE), yet few tools exist for risk stratification.
Sreekanth Vemulapalli, MD +13 more
doaj +5 more sources
International audienceBackground: There is an increased risk of arterial events including major adverse cardiovascular events (MACE) and major adverse limb events (MALE) after venous thromboembolism (VTE).
Nasr, Bahaa +15 more
core +4 more sources
High lipoprotein(a) is associated with major adverse limb events after femoral artery endarterectomy [PDF]
Backgrounds and aims: Elevated lipoprotein(a) (Lp[a]) has been identified as a causal risk factor for cardiovascular disease including peripheral arterial disease (PAD).
de Borst, Gert J. +13 more
core +5 more sources
Vorapaxar for Prevention of Major Adverse Cardiovascular and Limb Events in Peripheral Artery Disease [PDF]
Peripheral artery disease (PAD) is a severe manifestation of atherosclerosis. Patients with PAD are at heightened risk for atherothrombotic complications, including myocardial infarction and stroke (MACE); however, there is also an equal or greater risk ...
Justin T. Morrison MD +3 more
doaj +3 more sources
Cardiovascular risk factors and the risk of major adverse limb events in patients with symptomatic cardiovascular disease [PDF]
Aim: To determine the relationship between non-high-density lipoprotein cholesterol (non-HDL-c), systolic blood pressure (SBP) and smoking and the risk of major adverse limb events (MALE) and the combination with major adverse cardiovascular events (MALE/
Visseren, FLJ +6 more
core +6 more sources
Statins are guidelines recommended in patients with peripheral artery disease (PAD) for the prevention of cardiovascular (CV) events. Comprehensive meta-data on the impact of statins on major adverse limb events (MALE) in PAD patients are lacking.
Pastori, Daniele +6 more
core +6 more sources
PAD as a Marker of Systemic Atherosclerosis: A Comprehensive Review of Residual Risk and Contemporary Strategies for MACE and MALE Reduction [PDF]
Background: Peripheral artery disease (PAD) is a manifestation of systemic atherosclerosis associated with substantial risks of major adverse cardiovascular events (MACE) and major adverse limb events (MALE). Scope: This comprehensive review examines the
Giuseppe Miceli +4 more
doaj +2 more sources
© 2019 Elsevier Inc. Chronic coronary artery disease (CAD) and peripheral artery disease (PAD) are both associated with elevated risks of major adverse cardiovascular events (MACE) and major adverse limb events (MALE).
Bhagnani, Tarun +8 more
core +3 more sources
Association of Lipoprotein(a) Levels With Incidence of Major Adverse Limb Events.
ImportanceHigh lipoprotein(a) (Lp[a]) levels are involved in the development of cardiovascular events, particularly in myocardial infarction, stroke, and peripheral artery disease. Studies assessing the Lp(a) levels associated with adverse lower-limb events are lacking.ObjectiveTo assess the association between Lp(a) levels and incidence of major ...
Guédon AF +8 more
europepmc +3 more sources
Glucagon-like peptide-1 receptor agonists and major limb events in adults with type 2 diabetes and peripheral artery disease: a systematic review and meta-analysis of RCTs and cohort studies [PDF]
Background The impact of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on peripheral artery disease (PAD) remains uncertain. We assessed the association between GLP-1RA use and major limb events in individuals with type 2 diabetes (T2D) and PAD ...
Paola Caruso +7 more
doaj +2 more sources

