Results 191 to 200 of about 10,024,591 (280)

Utility of the Clinical Frailty Scale, Charlson Comorbidity Index and ACS NSQIP Surgical Risk Calculator in major lower limb orthopaedic surgery

Internal Medicine Journal, EarlyView.
Abstract Background With major lower limb orthopaedic surgery performed in increasingly older and comorbid patients, accurate risk prediction is essential to guide perioperative management and shared decision‐making. Aims To compare the Clinical Frailty Scale (CFS), Charlson Comorbidity Index (CCI) and the American College of Surgeons National Surgical
Alexa Yao, Emily Schembri, Ejoy Zhang, Raphael Hau, Christopher Fong   +4 more
wiley   +1 more source

Annual Research Review: A probe into sensitive periods – how the developmental timing of adverse childhood experiences influences brain structure and function – a systematic review

Journal of Child Psychology and Psychiatry, EarlyView.
It is proposed that adverse childhood experiences (ACEs) – potent predictors of mental illness – exert time‐dependent effects on neurodevelopment, reflecting periods of heightened neuroplasticity and developmental sensitivity. We systematically reviewed neuroimaging studies examining the role of timing in the association of ACE exposure with brain ...
Stephanie Hartanto, Divyangana Rakesh, Catherine Orr, Ebony Forlano, Muskan Khetan, Sarah Whittle   +5 more
wiley   +1 more source

Systemic Inflammatory Indices Predict Survival and Limb Outcomes after Revascularization for Chronic Limb-Threatening Ischemia.

J Vasc Res
Imbrognio F, Pepe I, Verastegui A, Gomez-Gutierrez OA, De la Torre OA, Gau R, Herrera-Vegas D, Fabiani MA.   +7 more
europepmc   +1 more source

Pulsatile Intravascular Lithotripsy for Heavily Calcified Femoropopliteal Arterial Disease: First-in-Human Results from the POWER PAD I Feasibility Study. [PDF]

J Clin Med
Mwipatayi BP, Lee BJ, Daudu D, Santana NE, Lansky A, Chisena RS, Gurm HS, Traficante R, George JC.   +8 more
europepmc   +1 more source

Influence of age on the development of stress hyperglycemia during first‐onset ST‐elevation myocardial infarction

Journal of Diabetes Investigation, EarlyView.
Among 8,779 non‐diabetic patients with first‐onset STEMI, older age was associated with a higher likelihood of stress hyperglycemia. However, the excess mortality risk associated with stress hyperglycemia was greatest in younger patients and attenuated with advancing age, highlighting the possibility of age‐dependent prognostic significance.
Hon Jen Wong, Joy Xin Yi Au, Yao Hao Teo, Yao Neng Teo, Chen Ee Low, Chun En Yau, Norman H.Y. Lin, Pei Chia Eng, Li Feng Tan, Reshma A. Merchant, Ping Chai, Anand Adinath Ambhore, James W. L. Yip, Andrew Fu‐Wah Ho, David Foo, Pow‐Li Chia, Patrick Zhan‐Yun Lim, Khung Keong Yeo, Weien Chow, Daniel Thuan Tee Chong, Derek J. Hausenloy, Mark Y. Y. Chan, Ching‐Hui Sia   +22 more
wiley   +1 more source

Safety and Clinical Performance of Peripherics™ Paclitaxel-Coated Balloon Catheter in Below-the-Knee Arteries: A Multicenter Post-market Study. [PDF]

Cureus
Sarda P, Gupta P, Burli P, Luthra L, Bedi V.   +4 more
europepmc   +1 more source

WTAP‐mediated m6A RNA methylation promotes diabetic foot ulcer healing under negative pressure wound therapy

Journal of Diabetes Investigation, EarlyView.
NPWT significantly increases the suppressed WTAP and m6A levels in DFU patients, correlating directly with better 4‐week healing outcomes. In vitro, negative pressure reverses high‐glucose‐induced WTAP downregulation, restoring the cell proliferation and migration necessary for wound repair.
Yutong Li, Wenhua Chen, Jianhao Lu, Xiaoyue Lin, Ying Tang, Jiaxu Li, Mingwei Chen   +6 more
wiley   +1 more source

Frailty and the efficacy and safety of surgical versus endovascular revascularization: post-hoc analysis of the BEST-CLI trial. [PDF]

Br J Surg
Ko D, Evans PT, Park CM, Kato B, Van Over M, Conte MS, Cziraky M, Shah SJ, Pande AN, Hamburg NM, Rosenfield K, Menard MT, Farber A, Kim DH.   +13 more
europepmc   +1 more source

Association between thyroid feedback quantile‐based index and the risk of in‐hospital amputation in patients with diabetic foot ulcer

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims To investigate the relationship between the thyroid feedback quantile‐based index (TFQI) and the risk of amputation during hospitalization in patients with diabetic foot ulcers (DFU). Methods This single‐center retrospective study included 381 hospitalized patients with DFU and normal thyroid function.
Jiale Wang, Yujie Huang, Funeng Wang, Meiling Lao, Lijun Lan, Peiling Liang   +5 more
wiley   +1 more source

Endoscopically-assisted in-situ lower limb arterial reconstruction is safe and effective: A retrospective cohort study. [PDF]

J Vasc Surg Cases Innov Tech
Klapman S, Kirkham AM, Licht J, Yacob M.
europepmc   +1 more source