Results 201 to 210 of about 10,024,591 (280)

A randomized phase 2 trial of socrodeucitinib in moderate‐to‐severe plaque psoriasis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In moderate‐to‐severe plaque psoriasis, socrodeucitinib (6 mg/12 mg) significantly outperformed placebo at week 12: PASI 75 response rates 28.6%/72.1% vs. 7.5%. Meanwhile, socrodeucitinib illustrated a favourable safety and tolerability profile, warranting further study.
Ling Han, Songmei Geng, Yangfeng Ding, Shifa Zhang, Xiaohua Wang, Fengming Hu, Jianguo Li, Chao Ci, Yayu Hu, Rixin Chen, Jianping Zhang, Xiaoyong Zhou, Aijun Chen, Chunlei Zhang, Tiechi Lei, Yanyan Feng, Yu Wang, Zudong Meng, Yan Zhou, Mingkai Ji, Wei Liu, Yunting Wu, Qianying Chen, Siyi Wang, Jinhua Xu   +24 more
wiley   +1 more source

The Quality of Life Impact of Vascular Anomalies on Patients and Their Families: Experience of a Tertiary Australian Centre

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim Chronic paediatric conditions often significantly impact the patients' and their families' quality of life (QoL). There is a paucity in the medical literature around the QoL impact of paediatric vascular anomalies on patients and their families in the Australian context. This study aims to address this gap.
Kwan Lam (Genevieve) Chow, Gloria Fong, Kelvin Truong, William Luu, Li‐Chuen Wong   +4 more
wiley   +1 more source

Preoperative Medical Evaluation and Optimisation of Children and Adolescents With Cerebral Palsy (GMFCS IV and V) With Complex Medical Comorbidity Undergoing Lower Limb Orthopaedic Surgery: Results of a Combined Rehabilitation Orthopaedic Paediatric Service

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim To describe preoperative medical evaluation, optimisation and acute postoperative outcomes in children and adolescents with cerebral palsy (CP) undergoing lower limb orthopaedic surgery managed in a Combined Rehabilitation Orthopaedic Paediatric Service (CROPS). Methods A retrospective medical record review of children and adolescents with
Jennifer Armstrong, Emre Ilhan, Verity Pacey, Paula Bray, Matthias Axt, Jacqueline Dalby‐Payne   +5 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Balancing Days at Home and Major Adverse Limb Events After Surgical Versus Endovascular Lower-Extremity Revascularization in Chronic Kidney Disease. [PDF]

J Am Heart Assoc
Chang TI, Parvathinathan G, Liu S, Lee JY, Etemadi A, Arya S, Stedman MR.   +6 more
europepmc   +1 more source

Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang, Geeta Madhuri Bhuvanagiri, Megan Dulkanchainun, Cunyu Wang   +3 more
wiley   +1 more source

Rheopheresis in hemodialysis patients with limb ulcers or amputation: safety and outcomes from a multicenter cohort. [PDF]

BMC Nephrol
Bonsante Y, Ferdynus C, Asgarali E, Di Ascia L, Vacher-Coponat H, Allal A, Baillet A, Gruget G, Delelis S, Veerapen R, Gayon J, Bennani HN, Le Flecher A.   +12 more
europepmc   +1 more source

Assessment of the long‐term outcomes of compartmental excision for treatment of infiltrative lipomas

Journal of Small Animal Practice, EarlyView.
Objectives To describe the post‐operative long‐term outcomes including recurrence rate of infiltrative lipoma in dogs following compartmental resection compared to debulking. Materials and Methods Twenty‐nine client‐owned dogs were surgically treated for infiltrative lipoma diagnosed on histopathology or diagnostic imaging with consistent appearance at
C. Tindale, A. C. Major, M. A. Pilot, S. J. Langley‐Hobbs, T. Hernon, E. J. Friend, L. B. Meakin   +6 more
wiley   +1 more source

Platelet Reactivity and Sex Differences: Clinical Implications for Women. [PDF]

Circ Res
Aggarwal A, Barrett TJ, Mehta PK, Honigberg MC, Cosemans JMEM, Goodman WA, Aggarwal NR, Holinstat M, Cho L, Cameron SJ, ACC Cardiovascular Disease in Women Committee.   +10 more
europepmc   +1 more source

Higher early radiographic bone healing scores with popliteus muscle preservation during tibial plateau levelling osteotomy in dogs

Journal of Small Animal Practice, EarlyView.
Objective To compare early radiographic bone healing 45 days after tibial plateau levelling osteotomy performed with popliteus muscle detachment versus a modified technique preserving the muscle and to determine whether muscle preservation influences post‐operative osteotomy stability through measurement of rock‐back.
S. Sassaroli, A. Salvaggio, F. Roggiolani, M. Fordellone, F. Ciabocco, A. Palumbo Piccionello   +5 more
wiley   +1 more source